Comparison of Titanium Vascular Closure Staples With Suture Repair of the Thoracic Aorta in Swine

Autor: Subrato J. Deb, E. Pikoulis, David C. Wherry, Barry D. Martin, Peter Rhee, David Burris, Leon Sun
Rok vydání: 2000
Předmět:
Zdroj: Chest. 118:1762-1768
ISSN: 0012-3692
DOI: 10.1378/chest.118.6.1762
Popis: Objective: Devices that reduce technical difficulty andanastigmatic time when repairing large vessels such as the thoracicaorta would be beneficial. The aim of this study was to determine iftitanium vascular closure staples (3 mm) could be safely and quicklyapplied in the repair of large vessels such as the thoracic aorta. Design: Through a left thoracotomy in 10 female swine (110to 130 lb), an interposition graft (14 to 16 mm textile) was placedinto the aorta distal to the left subclavian artery. Animals wererandomized at the time of repair to either running sutures (n = 5;6–0 polypropylene) or vascular closure staples (n = 5; 3 mm). Theanastomosis was evaluated after 2 months with aortograms, and the aortawas harvested to evaluate healing. Results: The clamptimes (mean ± SD) were 30.8 ± 8.2 min for suture repair and24.8 ± 5.1 min for vascular closure staple repair (p = 0.2).Anastomosis times were 20.0 ± 6.2 min for the suture group and16.4 ± 6.4 min for the vascular closure staple group (p = 0.4).Arch aortograms at 2 months revealed no significant difference inluminal narrowing between the two groups. Gross and microscopicexamination revealed no thrombosis, well-healed wounds with acontinuous intimal layer, and no differences in intimal thickness orinflammation between the two groups. Conclusion: Vascular closure staples were equivalent to sutures in terms ofdurability, graft patency, and wound healing at 2 months. Vascularclosure staples may offer the trauma surgeon a quick and easyalternative when repairing large vessels such as the thoracicaorta.
Databáze: OpenAIRE