Association between obesity categories with cardiovascular disease and its related risk factors in the MASHAD cohort study population

Autor: Fatemeh Saeidi, Ali Asghar Mahmoudi, Hamideh Ghazizadeh, Marziyeh Eidi, Reza Zare-Feyzabadi, Seyed Mostafa Parizadeh, Seyed Mohammad Reza Mirinezhad, Mohammad Reza Oladi, Mehran Yadegari, Habibollah Esmaily, Majid Ghayour-Mobarhan, Zahra Asadi, Ehsan Mosa Farkhany, Niloofar Shabani, Gordon A. Ferns, Mohsen Mouhebati, Mohadeseh Rohban, Payam Sharifan
Jazyk: angličtina
Rok vydání: 2019
Předmět:
0301 basic medicine
Male
cardiovascular risk factors
obesity
Clinical Biochemistry
Iran
Body Mass Index
0302 clinical medicine
Risk Factors
Immunology and Allergy
Research Articles
Metabolic Syndrome
education.field_of_study
Hematology
Middle Aged
Medical Laboratory Technology
Cardiovascular Diseases
030220 oncology & carcinogenesis
Hypertension
Female
Waist Circumference
Cohort study
Research Article
Microbiology (medical)
Adult
medicine.medical_specialty
Population
03 medical and health sciences
Diabetes mellitus
Internal medicine
medicine
Diabetes Mellitus
Humans
education
Triglycerides
Aged
Dyslipidemias
business.industry
Biochemistry (medical)
Cholesterol
HDL
Public Health
Environmental and Occupational Health
Odds ratio
medicine.disease
Obesity
R1
030104 developmental biology
Metabolic syndrome
business
Body mass index
Dyslipidemia
Zdroj: Journal of Clinical Laboratory Analysis
ISSN: 0887-8013
Popis: Background: Cardiovascular disease (CVD) is a significant cause of morbidity and mortality globally. Obesity is an important CVD risk factor and is increasing in prevalence. Methods: In this study, 3829 men and 5720 women (35-65 years) were enrolled as part of the MASHAD cohort study. Four categories were identified according to body mass index and waist circumference that was defined by the World Health Organization. Logistic regression analysis was used to determine the adjusted odds ratio (OR) for the occurrence of CVD, and Cox regression model was used to evaluate the association of obesity with CVD incidence. Results: We found that the higher risk groups defined by categories of adiposity were significantly related to a higher prevalence of a high serum total cholesterol (TC), and triglycerides (TG), and lower high-density lipoprotein cholesterol (HDL), and higher fasting blood glucose (FBG) in both genders and a higher low-density lipoprotein cholesterol (LDL) in women (P
Databáze: OpenAIRE
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