Altered expression of the tetraspanin CD81 on B and T lymphocytes during HIV-1 infection
| Autor: | Massimo Galli, Barbara Menzaghi, Luca Meroni, Agostino Riva, Renata Mazzucchelli, V. Broggini, Daniela Mologni, Paola Morelli, Fulvio Adorni, L. Milazzo |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
CD4-Positive T-Lymphocytes Male CD3 T cell viruses Immunology T lymphocytes Lymphoproliferative disorders HIV Infections chemical and pharmacologic phenomena Hepacivirus Biology Tetraspanin 28 Immune system CD81 Antigen Antigens CD Clinical Studies medicine Immunology and Allergy Humans RNA Messenger Analysis of Variance B-Lymphocytes lymphoproliferative disorders Reverse Transcriptase Polymerase Chain Reaction CD28 virus diseases T lymphocyte Middle Aged biochemical phenomena metabolism and nutrition medicine.disease Flow Cytometry HIV infection Hepatitis C biological factors HCV infection medicine.anatomical_structure Gene Expression Regulation Case-Control Studies biology.protein HIV-1 Female B lymphocytes |
| Zdroj: | Clinical and experimental immunology (2007). info:cnr-pdr/source/autori:L. Meroni, L. Milazzo, B. Menzaghi, R. Mazzucchelli, D. Mologni, P. Morelli, V. Broggini, F. Adorni, M. Galli and A. Riva/titolo:Altered expression of the tetraspanin CD81 on B and T lymphocytes during HIV-1 infection/doi:/rivista:Clinical and experimental immunology (Print)/anno:2007/pagina_da:/pagina_a:/intervallo_pagine:/volume 147 (2007): 53–59. doi:10.1111/j.1365-2249.2006.03250.x info:cnr-pdr/source/autori:Meroni, L.; Milazzo, L.; Menzaghi, B.; Mazzucchelli, R.; Mologni, D.; Morelli, P.; Broggini, V.; Adorni, F.; Galli, M.; Riva, A./titolo:Altered expression of the tetraspanin CD81 on B and T lymphocytes during HIV-1 infection/doi:10.1111%2Fj.1365-2249.2006.03250.x/rivista:Clinical and experimental immunology (Print)/anno:2007/pagina_da:53/pagina_a:59/intervallo_pagine:53–59/volume:147 |
| DOI: | 10.1111/j.1365-2249.2006.03250.x |
| Popis: | SummaryCD81 is a member of the tetraspan superfamily and plays a role in immune responses and in hepatitis C virus (HCV) pathogenesis. We analysed CD81 cell surface and mRNA expression in different lymphocytic subpopulations in human immunodeficiency virus (HIV)-1, HCV and dually infected subjects. CD81 cell surface expression was evaluated with fluorescence activated cell sorter (FACS) analysis; mRNA quantification was performed with semiquantitative polymerase chain reaction (PCR). CD81 cell surface expression on CD4+ T lymphocytes was significantly different by analysis of variance (anova) test (P |
| Databáze: | OpenAIRE |
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