Risk Factors Associated With Perioperative Complications and Prolonged Length of Stay After Laparoscopic Adrenalectomy

Autor: Insoo Suh, Kathryn Chomsky-Higgins, Carolyn D. Seib, Iheoma Nwaogu, Quan-Yang Duh, Anouk Scholten, Jessica E. Gosnell, Wen T. Shen, Yufei Chen
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Aging
Adrenal disorder
medicine.medical_treatment
Blood Loss
Surgical

Adrenal Gland Neoplasms
Comorbidity
030230 surgery
California
Cohort Studies
0302 clinical medicine
Postoperative Complications
Risk Factors
Surgical
80 and over
Blood Loss
Intraoperative Complications
Child
Cancer
Aged
80 and over

Academic Medical Centers
Age Factors
Adrenalectomy
Middle Aged
Conversion to Open Surgery
Child
Preschool

030220 oncology & carcinogenesis
Cohort
Female
Patient Safety
6.4 Surgery
Cohort study
Adult
medicine.medical_specialty
Adolescent
Clinical Trials and Supportive Activities
and over
Pheochromocytoma
03 medical and health sciences
Young Adult
Clinical Research
medicine
Diabetes Mellitus
Humans
Blood Transfusion
Preschool
Retrospective Studies
Aged
business.industry
Evaluation of treatments and therapeutic interventions
Retrospective cohort study
Odds ratio
Perioperative
Length of Stay
medicine.disease
Surgery
Laparoscopy
business
Zdroj: Chen, Y; Scholten, A; Chomsky-Higgins, K; Nwaogu, I; Gosnell, JE; Seib, C; et al.(2018). Risk Factors Associated With Perioperative Complications and Prolonged Length of Stay After Laparoscopic Adrenalectomy.. JAMA surgery. doi: 10.1001/jamasurg.2018.2648. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1865p3b3
JAMA surgery, vol 153, iss 11
DOI: 10.1001/jamasurg.2018.2648.
Popis: ImportanceLaparoscopic adrenalectomy is the gold standard for most adrenal disorders and its frequency in the United States is increasing. While national and administrative databases can adjust for patient factors, comorbidities, and institutional variations, granular disease-specific data that may significantly influence the incidence of perioperative complications and length of stay (LOS) are lacking.ObjectiveTo investigate factors associated with perioperative complications and LOS after laparoscopic adrenalectomy.Design, setting, and participantsThis cohort study was carried out at a single academic medical center, with all patients who underwent laparoscopic adrenalectomy between 1993 and 2017 by the endocrine surgery department. Multivariable linear and logistic regression were used to obtain adjusted odds ratios (ORs).Main outcomes and measuresThe primary outcome was perioperative complications with a Dindo-Clavien grade of 2 or more. The secondary outcome was prolonged length of stay, defined as a stay longer than the 75th percentile of the overall cohort.ResultsWe identified 640 patients who underwent 653 laparoscopic adrenalectomies, of whom 370 (56.7%) were female. The median age was 51 (range, 5-88) years. A total of 76 complications with a Dindo-Clavien grade of 2 or more occurred in 55 patients (8.4%), with postoperative mortality in 2 patients (0.3%). The median hospital length of stay was 1 day (range, 0-32 days). Factors independently associated with increased complications were American Society of Anesthesiologists class 3 or 4 (OR, 2.78 [95% CI, 1.39-5.55]; P
Databáze: OpenAIRE