Radiological Latency in Pineal Germinoma: A Case Report and Literature Review

Autor: Ivan Chi Hin Siu, Noel Ching Yan Chan, Xian Lun Zhu, Ryan Pak to Yuen, Zhexi He, Danny Tat Ming Chan
Rok vydání: 2022
Předmět:
Zdroj: Neuroophthalmology
ISSN: 1744-506X
0165-8107
Popis: Suprasellar germinomas can present with non-diagnostic, or even normal results on imaging. The spectrum of reported cases ranges from normal imaging, thickened pituitary stalks, to discrete tumour growths. This similar phenomenon is less commonly seen in the pineal region, or bifocal germinomas, and the literature is sparse with only a few case series or reports mentioning a similar presentation of signs and symptoms preceding radiological evidence of diagnosis. We report a case of pineal germinoma presenting with dorsal midbrain syndrome with no evidence of tumour growth on initial imaging despite symptoms. For patients presenting with this clinical radiological latent period, follow-up imaging is useful to identify interval development of germinomas. This applies to patients with dorsal midbrain syndrome, or even other unexplained ophthalmoplegia, as the initial sign of pineal region germinoma, despite normal imaging.
Databáze: OpenAIRE
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