Radiochemical synthesis of 105gAg-labelled silver nanoparticles
| Autor: | Víctor F. Puntes, Giulio Cotogno, Federica Simonelli, Douglas Gilliland, Uwe Holzwarth, Çiğdem İçhedef, Neil Gibson, J. Piella Bagaria |
|---|---|
| Přispěvatelé: | European Commission |
| Rok vydání: | 2013 |
| Předmět: |
Materials science
Nanoparticle Bioengineering 02 engineering and technology 010501 environmental sciences 01 natural sciences Silver nanoparticle chemistry.chemical_compound Sodium borohydride Dynamic light scattering Nitric acid General Materials Science 0105 earth and related environmental sciences Radiolabelling General Chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Atomic and Molecular Physics and Optics Silver nitrate Radiotracers chemistry Transmission electron microscopy Modeling and Simulation Metal powder Silver nanoparticles 0210 nano-technology Nuclear chemistry |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| ISSN: | 1572-896X 1388-0764 |
| Popis: | A method for synthesis of radiolabelled silver nanoparticles is reported. The method is based on proton activation of silver metal powder, enriched in 107Ag, with a 30.7 MeV proton beam. At this proton energy 105gAg is efficiently created, mainly via the 107Ag(p,3n)105Cd → 105gAg reaction. 105gAg has a half-life of 41.29 days and emits easily detectable gamma radiation on decay to 105Pd. This makes it very useful as a tracing radionuclide for experiments over several weeks or months. Following activation and a period to allow short-lived radionuclides to decay, the powder was dissolved in concentrated nitric acid in order to form silver nitrate (AgNO3), which was used to synthesise radiolabelled silver nanoparticles via the process of sodium borohydride reduction. For comparison, non-radioactive silver nanoparticles were synthesised using commercially supplied AgNO3 in order to check if the use of irradiated Ag powder as a starting material would alter in any way the final nanoparticle characteristics. Both nanoparticle types were characterised using dynamic light scattering, zeta-potential and X-ray diffraction measurements, while additionally the non-radioactive samples were analysed by transmission electron microscopy and UV–Vis spectrometry. A hydrodynamic diameter of about 16 nm was determined for both radiolabelled and non-radioactive nanoparticles, while the electron microscopy on the non-radioactive samples indicated that the physical size of the metal NPs was (7.3 ± 1.4) nm. This study has been partially supported by the European Commission’s 7th Framework Programme project QualityNano under the contract agreement SP4-CAPACITIES- 2010-262163. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink