Ancient DNA reveals male diffusion through the Neolithic Mediterranean route

Autor: Lacan, Marie, Keyser, Christine, Ricaut, François-Xavier, Brucato, Nicolas, Duranthon, Francis, Guilaine, Jean, Crubézy, Eric, Ludes, Bertrand, Crubezy, E.
Přispěvatelé: Laboratoire d'Anthropobiologie ( LA ), École des hautes études en sciences sociales ( EHESS ) -Université Toulouse - Jean Jaurès ( UT2J ) -Université Toulouse III - Paul Sabatier ( UPS ), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire d'Anthropologie Moléculaire, Institut de Médecine Légale, Strasbourg, France ( IML ), Université Louis Pasteur - Strasbourg I, Anthropologie Moléculaire et Imagerie de Synthèse ( AMIS ), PRES Université de Toulouse-Centre National de la Recherche Scientifique ( CNRS ), Collège de France ( CDF ), Collège de France ( CdF ), Institute of Legal Medicine, Université Paris Descartes - Paris 5 ( UPD5 ), Laboratoire d'Anthropobiologie (LA), École des hautes études en sciences sociales (EHESS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Anthropologie Moléculaire, Institut de Médecine Légale, Strasbourg, France (IML), Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Toulouse III - Paul Sabatier (UT3), Collège de France (CdF (institution)), Université Paris Descartes - Paris 5 (UPD5), Centre National de la Recherche Scientifique (CNRS), Human Genetics, Muséum d'Histoire Naturelle de Toulouse, Collège de France (CDF), Collège de France (CdF), Institut de Médecine Légale - IML (Paris, France)
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Mediterranean climate
Time Factors
MESH: Geography
MESH: Emigration and Immigration
MESH : DNA
Population Dynamics
[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology
Polymerase Chain Reaction
MESH: Fossils
MESH: Mediterranean Region
MESH : DNA
Mitochondrial

0601 history and archaeology
MESH : Population Dynamics
MESH : Polymerase Chain Reaction
Genetics
0303 health sciences
education.field_of_study
Multidisciplinary
Geography
Fossils
Mediterranean Region
Human migration
MESH: DNA
MESH : Geography
06 humanities and the arts
MESH: European Continental Ancestry Group
Biological Sciences
Emigration and Immigration
Europe
[ SDV.GEN.GPO ] Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]
France
MESH : Time Factors
Mitochondrial DNA
Population
MESH : Europe
MESH: Genetics
Population

Context (language use)
Biology
DNA
Mitochondrial

White People
MESH : European Continental Ancestry Group
03 medical and health sciences
MESH : Emigration and Immigration
Repartition
Humans
education
MESH : France
MESH : Mediterranean Region
030304 developmental biology
060101 anthropology
MESH: Humans
[SDV.GEN.GPO]Life Sciences [q-bio]/Genetics/Populations and Evolution [q-bio.PE]
business.industry
MESH: Time Factors
MESH : Humans
MESH: DNA
Mitochondrial

MESH: Polymerase Chain Reaction
DNA
MESH: Population Dynamics
MESH : Genetics
Population

MESH: France
Lactase persistence
Genetics
Population

Ancient DNA
Evolutionary biology
[ SHS.ANTHRO-BIO ] Humanities and Social Sciences/Biological anthropology
MESH : Fossils
MESH: Europe
business
Zdroj: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (24), pp.9788-91. 〈10.1073/pnas.1100723108〉
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (24), pp.9788-91. ⟨10.1073/pnas.1100723108⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (24), pp.9788-9791. ⟨10.1073/pnas.1100723108⟩
ISSN: 0027-8424
1091-6490
DOI: 10.1073/pnas.1100723108〉
Popis: International audience; The Neolithic is a key period in the history of the European settlement. Although archaeological and present-day genetic data suggest several hypotheses regarding the human migration patterns at this period, validation of these hypotheses with the use of ancient genetic data has been limited. In this context, we studied DNA extracted from 53 individuals buried in a necropolis used by a French local community 5,000 y ago. The relatively good DNA preservation of the samples allowed us to obtain autosomal, Y-chromosomal, and/or mtDNA data for 29 of the 53 samples studied. From these datasets, we established close parental relationships within the necropolis and determined maternal and paternal lineages as well as the absence of an allele associated with lactase persistence, probably carried by Neolithic cultures of central Europe. Our study provides an integrative view of the genetic past in southern France at the end of the Neolithic period. Furthermore, the Y-haplotype lineages characterized and the study of their current repartition in European populations confirm a greater influence of the Mediterranean than the Central European route in the peopling of southern Europe during the Neolithic transition.
Databáze: OpenAIRE