Contemporary Understandings of Cardiovascular Disease After Cancer Radiotherapy: a Focus on Ischemic Heart Disease
| Autor: | Emefah Loccoh, Ajay Vallakati, Patrick Ruz, Daniel Addison, Jeremy Slivnick, Lisa Kim, Terence M. Williams, Ahmet S. Ayan, Reynaldo Sanchez, Ragavendra R. Baliga, Eric D. Miller, Uzoma Anaba |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Population Myocardial Ischemia Disease 030204 cardiovascular system & hematology Coronary artery disease 03 medical and health sciences 0302 clinical medicine Intervention (counseling) Neoplasms medicine Humans 030212 general & internal medicine Lung cancer education Intensive care medicine Early Detection of Cancer education.field_of_study Radiotherapy business.industry Cancer Sequela medicine.disease Cardiotoxicity Radiation therapy Cardiovascular Diseases Cardiology and Cardiovascular Medicine business |
| Zdroj: | Current cardiology reports. 22(11) |
| ISSN: | 1534-3170 |
| Popis: | Radiation-induced cardiovascular disease, including coronary artery disease, is a well-known sequela of radiation therapy and represents a significant source of morbidity and mortality for cancer survivors. This review examines current literature and guidelines to care for this growing population of cancer survivors. The development of radiation-induced ischemic heart disease following radiation can lead even to early cardiotoxicities, inclusive of coronary artery disease, which limit cancer treatment outcomes. These coronary lesions tend to be diffuse, complex, and proximal. Early detection with multimodality imaging and targeted intervention is required to minimize these risks. Early awareness, detection, and management of radiation-induced cardiovascular disease are paramount as cancer survivorship continues to grow. |
| Databáze: | OpenAIRE |
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