Trends of mastectomy and breast-conserving surgery and related factors in female breast cancer patients treated at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, 2009–2017: A retrospective cohort study
| Autor: | Bassam E. Yaghmoor, Hisham Z Alshehri, Mohammed I Koumu, Zuhoor K Al-Gaithy, Abed A Saqah, Khalid A Alshehri |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
education.field_of_study business.industry Breast surgery medicine.medical_treatment General surgery Population Retrospective cohort study General Medicine Modified Radical Mastectomy medicine.disease 03 medical and health sciences 0302 clinical medicine Breast cancer 030220 oncology & carcinogenesis medicine Breast-conserving surgery 030211 gastroenterology & hepatology Surgery Breast reconstruction education business Mastectomy Original Research |
| Zdroj: | Annals of Medicine and Surgery. 41:47-52 |
| ISSN: | 2049-0801 |
| DOI: | 10.1016/j.amsu.2019.03.012 |
| Popis: | Background Breast cancer is the most common cancer in women and accounts for 14.7% of cancer-related deaths among females worldwide. Its core management includes surgical removal of the tumor either by breast-conserving surgery (BCS) or mastectomy. Choosing between these two procedures may be influenced by factors that are not studied in our region. We aimed to determine the prevalence of BCS and mastectomy and the factors that may influence the choice of procedure. Methods This retrospective study was carried out by reviewing the records of female breast cancer patients who underwent BCS or mastectomy at between 2009 to June 2017, excluding those with metastasis or recurrence. Frequencies and multivariate tests were used for detecting correlations between procedures and demographic, clinicopathological, and radiological factors. Results Of 335 patients (mean age 52.75 ± 12.2 years), 62.4% had mastectomy and 37.6% had BCS. Modified radical mastectomy accounted for 70.8% of mastectomies. Multivariate analysis showed non-Saudi nationality (P = 0.002), multifocal (P = 0.0001) and multicentric tumors (P = 0.0001), large tumor size (P = 0.0001), tumor stages IIIA (P = 0.005) and IIIB (P = 0.014), positive HER2 (0.009), and triple-negative receptor status (P = 0.010) significantly correlated with mastectomy. Conclusion Mastectomy has a much higher prevalence than BCS in our study mainly due to advanced tumor stage at the time of diagnosis. This emphasizes the urgent need for early detection of breast cancer to move towards BCS, with education and increasing awareness of breast cancer and the surgical options, especially that it is more common in a significantly younger population in our area. |
| Databáze: | OpenAIRE |
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