Outcome of Repeated Use of Donor Site for Noncultured Epidermal Cellular Grafting in Stable Vitiligo: A Retrospective Study
| Autor: | Duangporn Saengwimol, Vasanop Vachiramon, Kumutnart Chanprapaph, Korn Triyangkulsri |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Article Subject Treatment outcome Vitiligo lcsh:Medicine Skin Pigmentation Transplantation Autologous General Biochemistry Genetics and Molecular Biology 030207 dermatology & venereal diseases 03 medical and health sciences Cicatrix 0302 clinical medicine Electronic records Dyschromia Medicine Humans Retrospective Studies General Immunology and Microbiology business.industry lcsh:R Retrospective cohort study Epithelial Cells General Medicine Middle Aged medicine.disease Dermatology Transplantation Treatment Outcome Epidermal Cells 030220 oncology & carcinogenesis Clinical Study Melanocytes Female Epidermis business |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2019 (2019) |
| ISSN: | 2314-6133 |
| DOI: | 10.1155/2019/7623607 |
| Popis: | Background. Noncultured epidermal suspension (NCES) is a surgical technique which employs cellular grafting onto depigmented lesions. However, scarring and dyschromia at the donor site often occurs. Objective. To assess the outcome of reusing the same donor site in subsequent sessions of NCES procedures. Methods. Electronic records of vitiligo patients who had undergone two sessions of NCES procedures were retrospectively reviewed. Information on the first and second NCES was retrieved for analyses. Results. A total of 30 patients (female 19 and male 11) were included. The majority of patients had nonsegmental vitiligo (66.7%). The median donor-to-recipient ratios were 1 : 3 (1 : 1–1 : 20) for the first session and 1 : 3 (1 : 1–1 : 13.5) for the second session (p=0.661). The mean melanocyte count was 220.7 ± 65.5 cells/mm2 vs. 242.4 ± 55.3 cells/mm2 on the first and second sessions, respectively (p=0.440). The mean repigmentation rate was 84.2% (±21.1%) and 82.3 (±22.1%) for the first and second NCESs, respectively (p=0.645). The frequency of color mismatch and pigment loss were similar between both sessions (p=0.706 and p=1.000). Conclusions. Repeated use of donor sites in subsequent NCES sessions gave comparable repigmentation. |
| Databáze: | OpenAIRE |
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