Effects of the three-dimensional residual stresses on the mechanical properties of arterial walls
| Autor: | Jiu-Sheng Ren, Xianbing Zheng |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Statistics and Probability Mean arterial pressure Materials science Arterial disease 0206 medical engineering Myocytes Smooth Muscle 02 engineering and technology Bending General Biochemistry Genetics and Molecular Biology Stress (mechanics) 03 medical and health sciences Smooth muscle Residual stress Pressure Humans Composite material General Immunology and Microbiology biology Applied Mathematics Models Cardiovascular General Medicine Arteries 020601 biomedical engineering Biomechanical Phenomena 030104 developmental biology Modeling and Simulation biology.protein Cylinder stress Stress Mechanical General Agricultural and Biological Sciences Tunica Intima Tunica Media Elastin |
| Zdroj: | Journal of theoretical biology. 393 |
| ISSN: | 1095-8541 |
| Popis: | Effects of the three-dimensional residual stresses on the mechanical properties of arterial walls are analyzed in this paper, based on the model which considered the bending and stretching both in the circumferential and axial directions of the three distinct arterial layers. Moreover, different constitutive models are proposed to quantify the nonlinear mechanics of the three distinct layers and the important constituents, i.e. elastin, collagen fibers and smooth muscle cells (SMCs), are all taken into account. The stress distributions and pressure-radius curves of the arterial wall are given in details. Results demonstrate that the maximum values of the circumferential stress and the corresponding stress gradient in the media under the mean arterial pressure are reduced significantly as a consequence of the SMCs. The bending in the axial direction of the media and the opening angle of the intima have an obvious impact on the mechanical behaviors of arterial walls. This study may not only develop the understanding of effects of the three-dimensional residual stresses on the arterial wall response, but also can increase the accuracy of the analyses for patient-specific studies used for the treatments of arterial diseases. |
| Databáze: | OpenAIRE |
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