| Autor: |
Roger Cooke, Kathy Franks-Skiba, Katherine Polosukhina, Kelly Duignan, Stefan Highsmith |
| Jazyk: |
angličtina |
| Předmět: |
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| Zdroj: |
Biophysical Journal. (6):3351 |
| ISSN: |
0006-3495 |
| DOI: |
10.1016/S0006-3495(99)77489-8 |
| Popis: |
In the accompanying letter to the editor, Dr. Grazi and his colleagues have suggested an alternative explanation for the interpretation of our recent study of the effects of immobilization on S1. They raise the possibility that the free [Mg2+] is reduced by binding to PEG, which reduces [MgATP], and that this accounts for the inhibition of MgATPase activity when S1 is aggregated by high [PEG]. While it is true that [Mg2+] binds to PEG in solution, a simple calculation demonstrates that the reduction in [MgATP] is not sufficient to account for the observed changes in S1 activity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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