Clinimetric properties and suitability of selected quality indicators for assessing antibiotic use in hospitalized adults: a multicentre point prevalence study in 24 hospitals in Germany
| Autor: | Gesche, Först, Winfried V, Kern, Nadine, Weber, Christiane, Querbach, Johannes, Kleideiter, Holger, Knoth, Stefan, Hagel, Andreas, Ambrosch, Micha, Löbermann, Philipp, Schröder, Johannes, Borde, Michaela, Steib-Bauert, Katja, de With, Enrico, Zessin |
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| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine Microbiology (medical) medicine.medical_specialty media_common.quotation_subject 030106 microbiology Bacteremia Pilot Projects Drug Prescriptions Antimicrobial Stewardship 03 medical and health sciences Surgical prophylaxis 0302 clinical medicine Case mix index Germany Acute care External quality assessment Prevalence medicine Humans Antimicrobial stewardship Pharmacology (medical) Quality (business) 030212 general & internal medicine Medical prescription Intensive care medicine Aged Quality Indicators Health Care Quality of Health Care media_common Pharmacology Inpatients business.industry Reproducibility of Results Guideline Middle Aged Hospitals Anti-Bacterial Agents Cross-Sectional Studies Infectious Diseases Urinary Tract Infections Female business |
| Zdroj: | Journal of Antimicrobial Chemotherapy. 74:3596-3602 |
| ISSN: | 1460-2091 0305-7453 |
| Popis: | Objectives The capability to measure and monitor the quality of antibiotic prescribing is an important component of antibiotic stewardship (ABS) programmes. Several catalogues of consensus-based structure and process-of-care quality indicators (QIs) have been proposed, but only a few studies have tested and validated ABS QIs in practice tests. This multicentre study determined the clinimetric properties and suitability of a set of 33 process QIs for ABS that had earlier been developed and in part recommended in a German–Austrian hospital ABS practice guideline. Methods Two point prevalence surveys were conducted in a convenience sample of 24 acute care hospitals throughout Germany, and data of all screened adult inpatients with prescription of a systemic antibiotic at a given day (n=4310) were included in the study. For each QI, the following clinimetric properties were assessed: applicability, feasibility, performance, case mix stability and interobserver reliability. Results Eighteen QIs were considered sufficiently feasible, applicable and reliable, and had adequate room for improvement. The finally selected QIs primarily cover antibiotic therapy of common infections (bloodstream infection, pneumonia and urinary tract infection), while two of the QIs each address surgical prophylaxis and general aspects of antibiotic administration. Conclusions Practice tests may be important to test the suitability of consensus process-of-care QIs in the field of hospital ABS. The 18 selected QIs considered suitable enough for hospital ABS in this study should be regarded as priority QIs useful for internal quality control and assurance. More research and additional practice tests may be needed to confirm their suitability for external quality assessment schemes. |
| Databáze: | OpenAIRE |
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