Standardized bench test evaluation of coronary stents: Biomechanical characteristics

Autor: Francois Huchet, Jean Marc Olive, Patrice Guerin, Fabienne Jordana, Mickael Bonin
Přispěvatelé: Centre hospitalier universitaire de Nantes (CHU Nantes), unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS), Institut de Mécanique et d'Ingénierie (I2M), Université de Bordeaux (UB)-Institut Polytechnique de Bordeaux-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Arts et Métiers Sciences et Technologies, HESAM Université (HESAM)-HESAM Université (HESAM), Regenerative Medicine and Skeleton research lab (RMeS), Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Rok vydání: 2018
Předmět:
Compressive Strength
030204 cardiovascular system & hematology
Prosthesis Design
Bench test
Elastic recoil
[PHYS.MECA.MEMA]Physics [physics]/Mechanics [physics]/Mechanics of materials [physics.class-ph]
03 medical and health sciences
[SPI]Engineering Sciences [physics]
0302 clinical medicine
Percutaneous Coronary Intervention
Stent deployment
Materials Testing
Pressure
Medicine
Radiology
Nuclear Medicine and imaging
030212 general & internal medicine
cardiovascular diseases
[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/Biomaterials
Cardiovascular mortality
business.industry
Coronary anatomy
Drug-Eluting Stents
General Medicine
[PHYS.MECA.MSMECA]Physics [physics]/Mechanics [physics]/Materials and structures in mechanics [physics.class-ph]
equipment and supplies
Elasticity
Ambient air
Prosthesis Failure
Clinical Practice
surgical procedures
operative
Stress
Mechanical
Cardiology and Cardiovascular Medicine
business
Biomedical engineering
Zdroj: Catheterization and Cardiovascular Interventions
Catheterization and Cardiovascular Interventions, Wiley, 2018, 92 (7), pp.E465-E470. ⟨10.1002/ccd.27912⟩
ISSN: 1522-726X
1522-1946
DOI: 10.1002/ccd.27912⟩
Popis: International audience; Objectives The purpose of the study was to develop a standardized and global bench test protocol to evaluate the biomechanical characteristics of the most currently used drug-eluting coronary stents. Background The use of coronary stents has contributed to the reduction of cardiovascular mortality but can be associated with specific complications. Improving the biomechanical matching between the stents and the coronary anatomy may reduce these complications. Methods We assessed five commercially available drug-eluting stents: the Absorb, Orsiro, Resolute Onyx, Synergy, and Xience Alpine stents. Following stent deployment at nominal pressure in ambient air, radial elastic recoil and foreshortening were measured. Flexibility (crimped and deployed stents) and longitudinal and radial resistances were evaluated using a mechanical tester. Results Biomechanical characteristics were significantly different for all tested devices (ANOVA, P < 0.01). The Synergy, Orsiro, and Xience Alpine stents presented the lowest elastic recoil. The Synergy and Resolute Onyx stents were the most flexible devices. The Xience Alpine and Absorb stents had the highest longitudinal and radial resistances. Conclusions Drug-eluting coronary stents used in current clinical practice have very different biomechanical characteristics, which should be taken into consideration to select the most appropriate device for each clinical situation.
Databáze: OpenAIRE
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