Human leptospirosis cases and the prevalence of rats harbouring Leptospira interrogans in urban areas of Tokyo, Japan
Autor: | Maki Muto, Yoshiko Sohmura, Tsutomu Tanikawa, Nobuo Koizumi, Hiroshi Mizutani, Eiji Hayashi, Nobuaki Akao, Mayu Hoshino, Haruo Watanabe, Hiroki Kawabata |
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Rok vydání: | 2009 |
Předmět: |
Microbiology (medical)
Serotype Veterinary medicine Disease reservoir Molecular Sequence Data Prevalence Inner Cities Microbiology Rodent Diseases Zoonoses Leptospiraceae medicine Animals Humans Leptospirosis Tokyo Leptospira interrogans serovar Copenhageni Disease Reservoirs biology business.industry Urban Health General Medicine biology.organism_classification medicine.disease Rats Carrier State Leptospira interrogans business geographic locations |
Zdroj: | Journal of Medical Microbiology. 58:1227-1230 |
ISSN: | 1473-5644 0022-2615 |
DOI: | 10.1099/jmm.0.011528-0 |
Popis: | Thirteen patients with leptospirosis were identified, as confirmed by laboratory analysis during the last 5 years in our laboratory, who came from urban areas of Tokyo, Japan. All of the patients came into contact with rats before the onset of illness. Seventeen per cent of Norway rats captured in the inner cities of Tokyo carried leptospires in their kidneys. Most of these rat isolates were Leptospira interrogans serovar Copenhageni/Icterohaemorrhagiae. Antibodies against these serovars and their DNA were detected in the patients. This suggests that rats are important reservoirs of leptospirosis, and that rat-borne leptospires occur in urban areas of Tokyo. |
Databáze: | OpenAIRE |
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