Human leptospirosis cases and the prevalence of rats harbouring Leptospira interrogans in urban areas of Tokyo, Japan

Autor: Maki Muto, Yoshiko Sohmura, Tsutomu Tanikawa, Nobuo Koizumi, Hiroshi Mizutani, Eiji Hayashi, Nobuaki Akao, Mayu Hoshino, Haruo Watanabe, Hiroki Kawabata
Rok vydání: 2009
Předmět:
Zdroj: Journal of Medical Microbiology. 58:1227-1230
ISSN: 1473-5644
0022-2615
DOI: 10.1099/jmm.0.011528-0
Popis: Thirteen patients with leptospirosis were identified, as confirmed by laboratory analysis during the last 5 years in our laboratory, who came from urban areas of Tokyo, Japan. All of the patients came into contact with rats before the onset of illness. Seventeen per cent of Norway rats captured in the inner cities of Tokyo carried leptospires in their kidneys. Most of these rat isolates were Leptospira interrogans serovar Copenhageni/Icterohaemorrhagiae. Antibodies against these serovars and their DNA were detected in the patients. This suggests that rats are important reservoirs of leptospirosis, and that rat-borne leptospires occur in urban areas of Tokyo.
Databáze: OpenAIRE