Smith-Magenis syndrome: A case report of improved sleep after treatment with β1-adrenergic antagonists and melatonin

Autor:	Araceli Abad, Emilio J. Sánchez-Barceló, Rosario Carpizo, Ángeles Martínez, Mónica González, Dolores Mediavilla
Rok vydání:	2006
Předmět:	Male endocrine system medicine.medical_specialty Evening medicine.medical_treatment Adrenergic beta-Antagonists Acebutolol Antioxidants Melatonin Sleep Disorders Circadian Rhythm Internal medicine medicine Adrenergic antagonist Humans Morning Chronotherapy business.industry Chronotherapy (sleep phase) Antagonist Syndrome Smith–Magenis syndrome medicine.disease Endocrinology Child Preschool Pediatrics Perinatology and Child Health Chromosome Deletion business hormones hormone substitutes and hormone antagonists Chromosomes Human Pair 17 medicine.drug
Zdroj:	The Journal of Pediatrics. 149:409-411
ISSN:	0022-3476
DOI:	10.1016/j.jpeds.2006.04.055
Popis:	This report describes the case of a 4-year-old boy diagnosed with Smith-Magenis syndrome in whom treatment with a beta(1)-adrenergic antagonist in the morning (to suppress the diurnal melatonin secretion) and melatonin in the evening (to generate a nocturnal peak of melatonin) improved his sleep quality, evaluated by polysomnographic studies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6796a81004894d1394ad5d5b8aadebf0 https://doi.org/10.1016/j.jpeds.2006.04.055 Zobrazit plný text záznamu Full Text from ScienceDirect