Related and unrelated donor transplantation for β-thalassemia major: results of an international survey

Autor: Hua Jiang, Rajni Agarwal, Jeffery J. Auletta, Kyle Hebert, Christopher C. Dvorak, Mary Eapen, Biju George, Rabi Hanna, Vikram Mathews, Angela R. Smith, Mark C. Walters, Daniel A. Keesler, Jaap Jan Boelens, Shalini Shenoy, Changgang Li, Rakesh K. Goyal, Kimberly A. Kasow, Yiping Zhu, Chunfu Li, Soyoung Kim
Rok vydání: 2019
Předmět:
Zdroj: Blood advances, vol 3, iss 17
Popis: We studied 1110 children, adolescents and young adults with β thalassemia major transplanted with grafts from HLA-matched relative (n=677; 61%), HLA-mismatched relative (n=78; 7%), HLA-matched unrelated (n=252; 23%) and HLA-mismatched unrelated (n=103; 9%) donors in 2000 - 2016. The median age at transplantation was 6 years (range Disclosures Dvorak: Jazz Pharmaceuticals: Consultancy; Chimerix, Inc.: Membership on an entity's Board of Directors or advisory committees. Shenoy:Novartis, Vertex, Bluebird Bio: Honoraria, Membership on an entity's Board of Directors or advisory committees. Walters:Sangamo Therapeutics: Consultancy; bluebird bio: Research Funding; ViaCord Processing Lab: Other: Medical Director; AllCells Inc.: Other: Medical Director.
Databáze: OpenAIRE