Synthesis and conformational preferences of cyclic unnatural di- and tripeptides containing an l-valine unit: Part 2
| Autor: | Sergio Sandri, Enrico Emer, Daniele Balducci, Gianni Porzi, Fabio Piccinelli, Maurizio Recanatini |
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| Přispěvatelé: | D. Balducci, E. Emer, F. Piccinelli, G. Porzi, M. Recanatini, S. Sandri |
| Rok vydání: | 2005 |
| Předmět: |
CYCLIC UNNATURAL DI- AND TRI-PEPTIDES
STEREOCONTROLLED SYNTHESIS Stereochemistry Chemistry Organic Chemistry Synthon X-RAY-ANALYSIS Tripeptide Catalysis Inorganic Chemistry 6-DIAMINOPIMELIC ACID FRAMEWORK Valine STEREOSELECTIVE SYNTHESIS Proton NMR Stereoselectivity 2 Physical and Theoretical Chemistry CONFORMATIONAL PREFERENCES OF CYCLIC UNNATURAL DI- AND TRI-PEPTIDES X ray analysis |
| Zdroj: | Tetrahedron: Asymmetry. 16:3785-3794 |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/j.tetasy.2005.10.030 |
| Popis: | Stereoselective syntheses of non-proteinogenic di- 14a , b , 15a , b and 16a , b and tripeptides 14c , 15c and 16c containing an l -valine unit and a cyclic unnatural α-amino acid have been accomplished starting from the l -valine derived chiral synthon 1 . The conformational preferences of these unnatural peptides were investigated by 1 H NMR and IR spectroscopies and by molecular modelling calculations. X-ray analysis of pseudopeptides 15a and 15b is also reported. |
| Databáze: | OpenAIRE |
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