Antioxidant activity of the methanolic extract of the newly generated vegetable, baemuchae (xBrassicoraphanus)
| Autor: | Jongkee Kim, So-Youn Mok, Mi Jin Choi, Sanghyun Lee, Eun Ju Cho |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Magnetic Resonance Spectroscopy
Antioxidant Swine Radical medicine.medical_treatment Brassica Toxicology medicine.disease_cause High-performance liquid chromatography Antioxidants Ferulic acid chemistry.chemical_compound medicine Animals Viability assay Chromatography High Pressure Liquid Plant Extracts urogenital system Chemistry Methanol General Medicine In vitro Oxidative Stress Biochemistry Calibration Shoot LLC-PK1 Cells Spectrophotometry Ultraviolet Oxidative stress Food Science |
| Zdroj: | Food and Chemical Toxicology. 50:848-853 |
| ISSN: | 0278-6915 |
| DOI: | 10.1016/j.fct.2012.01.006 |
| Popis: | We investigated the radical scavenging activity and protective effects of the methanol extract (ME) and ferulic acid (FA) from baemuchae (xBrassicoraphanus) against oxidative stress in vitro and on a cellular system using LLC-PK1 renal epithelial cells. In vitro, ME and FA showed dose-dependent radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl and hydroxyl radicals. LLC-PK1 cells displayed decreased viability in response to nitric oxide-induced oxidative stress. However, ME and FA significantly increased LLC-PK1 cell viability in a dose-dependent manner. Based on HPLC/UV analysis, the FA content was higher in the shoot of baemuchae than in the root. The results of the present study suggest that baemuchae may be a promising source of antioxidants against oxidative stress induced by free radicals. |
| Databáze: | OpenAIRE |
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