Association between polypharmacy and health-related quality of life among cancer survivors in the United States
| Autor: | Stephen Kogut, Ami Vyas, Zachary R. Babcock |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent 03 medical and health sciences Young Adult 0302 clinical medicine Quality of life Cancer Survivors Neoplasms medicine Humans 030212 general & internal medicine Medical prescription Socioeconomic status Aged Health related quality of life Polypharmacy Oncology (nursing) business.industry Public health Cancer Middle Aged medicine.disease humanities United States Cross-Sectional Studies Oncology 030220 oncology & carcinogenesis Quality of Life Female business Medical Expenditure Panel Survey human activities Demography |
| Zdroj: | Journal of cancer survivorship : research and practice. 14(1) |
| ISSN: | 1932-2267 |
| Popis: | Polypharmacy (PP) is present in many cancer survivors and may lead to lower health-related quality of life (HRQoL). The study’s objective was to evaluate the association between PP and HRQoL among cancer survivors in the US. A cross-sectional analysis of the Medical Expenditure Panel Survey (MEPS) was conducted. Our analytic sample included all adult patients with cancer, during even years 2008–2014. PP was defined as reported use of five or more unique therapeutic classes of prescription medications. The MEPS measured HRQoL using the Short Form 12-Item Health Survey Version 2 (SF-12v2) physical component summary (PCS) and mental component summary (MCS) scores. Ordinary least squares regressions were used to assess associations between PP and HRQoL controlling for demographic, socioeconomic, and clinical factors. PP was prevalent among 44.4% of 10.1 million cancer survivors per calendar year (on average) for years 2008, 2010, 2012, and 2014. The mean adjusted PCS score for cancer survivors with PP was 35.8 points, which was significantly lower compared with cancer survivors without PP (39.5) by 3.7 points (p value |
| Databáze: | OpenAIRE |
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