Predictors of abnormal cytology among HPV-infected women in remote territories of French Guiana
| Autor: | Jerome Ponty, Raymond Césaire, Nadia Thomas, Vincent Molinie, Claire Grenier, Valentin Dufit, Maylis Douine, Laure Bianco, Mathieu Nacher, Paul Brousse, Antoine Adenis, Dominique Catherine, Gabriel Carles, Fatiha Najioullah, Odile Kilié, Jean Luc Deshayes, Vincent Lacoste |
|---|---|
| Přispěvatelé: | Centre d'investigation clinique Antilles-Guyane (CIC - Antilles Guyane), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre/Abymes [Guadeloupe] -CHU de la Martinique [Fort de France]-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Laboratoire de Virologie-Immunologie [Fort de France, Martinique] (EA 4537), Centre Hospitalier Universitaire de Martinique [Fort-de-France, Martinique], Service d'anatomopathologie [Fort de France, Martinique], CHU Fort de France, Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Association Guyanaise Dépistage Organisé des Cancers [Cayenne] (A.G.D.O.C), Département des Centres Délocalisés de Prévention et de Soins [Cayenne, Guyane Française], Centre Hospitalier de l'Ouest Guyanais Franck Joly [Saint-Laurent-du-Maroni, Guyane Française], Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française], Institut Pasteur de la Guyane, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), The present study was funded by the European Regional Development Funds (FEDER) N° Presage 30,814., Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU de la Martinique [Fort de France]-CHU Pointe-à-Pitre/Abymes [Guadeloupe] -Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française] |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Rural Population
[SDV]Life Sciences [q-bio] Uterine Cervical Neoplasms MESH: Genotype 0302 clinical medicine MESH: Rural Population [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Cytology Genotype Medicine 030212 general & internal medicine Life history Papillomaviridae Anamnesis MESH: Aged MESH: Middle Aged lcsh:Public aspects of medicine Obstetrics and Gynecology virus diseases General Medicine MESH: Papillomavirus Vaccines Middle Aged Abnormal cytology female genital diseases and pregnancy complications MESH: Predictive Value of Tests 3. Good health French Guiana Vaccination MESH: Young Adult 030220 oncology & carcinogenesis [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Female MESH: Papillomavirus Infections/complications MESH: DNA Viral/analysis Research Article Adult medicine.medical_specialty Cytodiagnosis Reproductive medicine [SDV.CAN]Life Sciences [q-bio]/Cancer MESH: Papillomavirus Infections/prevention & control lcsh:Gynecology and obstetrics MESH: Papillomaviridae/isolation & purification MESH: Cytodiagnosis/statistics & numerical data 03 medical and health sciences Young Adult Predictive Value of Tests Internal medicine MESH: French Guiana Humans Papillomavirus Vaccines MESH: Papillomaviridae/genetics Normal cytology lcsh:RG1-991 Aged MESH: Uterine Cervical Neoplasms/virology MESH: Humans business.industry Papillomavirus Infections MESH: Papillomavirus Infections/virology lcsh:RA1-1270 MESH: Adult Reproductive Medicine DNA Viral MESH: Uterine Cervical Neoplasms/prevention & control [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business MESH: Female |
| Zdroj: | BMC Women's Health BMC Women's Health, BioMed Central, 2018, 18 (1), ⟨10.1186/s12905-017-0493-9⟩ BMC Women's Health, Vol 18, Iss 1, Pp 1-7 (2018) |
| ISSN: | 1472-6874 |
| Popis: | International audience; BACKGROUND: Cervical cancer prevention using cervical cytology is insufficiently sensitive, a significant proportion of HPV-infected women having normal cytology. The objective of the present study was to try to identify factors associated with abnormal cytology in HPV-infected women living in remote areas of French Guiana.METHODS: A study was conducted in women aged 20-65 years having HPV infections confirmed by HPV DNA detection using the GREINER-BIO-ONE kit. In addition to HPV testing, cytology was performed and classified as normal or abnormal. Demographic and life history variables, and infecting genotypes were compared between the normal and abnormal cytology groups.RESULTS: None of the demographic and life history variables were associated with cytology results. HPV genotype 53 was significantly associated with absence of cytological abnormalities whereas HPV 52, 58, 16 and perhaps 33 and 66 were independently associated with a greater risk of cytological abnormalities. When grouping HPV genotypes in different species, only species 9 (HPV 16, 31, 33, 35, 52, 58, 67) was significantly associated with abnormal cytology AOR = 5.1 (95% CI = 2.3-11.2), P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink