Inherited hemorrhagic disorder with antihemophilic globulin deficiency and prolonged bleeding time (vascular hemophilia)
| Autor: | Carroll L. Spurling, Milton S. Sacks |
|---|---|
| Rok vydání: | 1959 |
| Předmět: |
Bleeding Time
medicine.diagnostic_test business.industry Hemorrhagic diathesis Genetic Diseases Inborn Physiology Globulins General Medicine Disease Hemophilia A Hemorrhagic Disorders Hemorrhagic disorder von Willebrand Diseases Prolonged bleeding time Bleeding time Immunology Medicine Antihemophilic globulin deficiency Antihemophilic globulin business |
| Zdroj: | The New England journal of medicine. 261(7) |
| ISSN: | 0028-4793 |
| Popis: | SINCE 1953 a number of reports seem to have established as a clinical entity a hereditary hemorrhagic disorder characterized by deficiency of antihemophilic globulin and a prolonged bleeding time. Despite the deficiency of antihemophilic globulin, the disease differs from classic hemophilia in several important ways: it occurs commonly in both sexes and thus follows an obviously different genetic pattern; the type of bleeding differs in that it is most often into the skin or from mucous membranes and rarely involves the joints; and the bleeding time is characteristically prolonged. Alexander and Goldstein,1 in 1953, first described the dual hemostatic defect . . . |
| Databáze: | OpenAIRE |
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