Endurance training increases the β-adrenergic lipolytic response in subcutaneous adipose tissue in obese subjects
| Autor: | Michel Berlan, I. De Glisezinski, J. Galitzky, François Crampes, J. Hejnova, Daniel Rivière, V. Stich |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Glycerol Male medicine.medical_specialty Microdialysis Phosphodiesterase Inhibitors Lipolysis Endocrinology Diabetes and Metabolism Medicine (miscellaneous) Adipose tissue Fatty Acids Nonesterified Theophylline Endurance training Internal medicine Isoprenaline Receptors Adrenergic beta Humans Medicine Aerobic exercise Obesity Exercise Nutrition and Dietetics business.industry Isoproterenol Adrenergic beta-Agonists Glucose Tolerance Test Middle Aged Lipids Endocrinology Adipose Tissue Physical Endurance business Perfusion medicine.drug |
| Zdroj: | International Journal of Obesity. 23:374-381 |
| ISSN: | 1476-5497 0307-0565 |
| Popis: | OBJECTIVE: The aim of this study was to assess, by longitudinal follow-up, the influence of aerobic training on the in vivo lipolytic activity of adipose tissue in obese male subjects. SUBJECTS: Eleven obese non-diabetic males, aged 41.5±5.7 7 (range 27–49 y) with body mass index (BMI) 36.5±4.5 kg\m2 (range 29.4–47.1 kg\m2) participated in the study. DESIGN: Subjects took part in a 12-week aerobic training program. Before and after training, microdialysis of abdominal subcutaneous adipose tissue (SCAT) was carried out, using perfusion with graded doses of the β β-adrenergic agonist isoprenaline and a single dose of the phosphodiesterase inhibitor theophylline. In addition, the response of plasma glycerol and free fatty acids (FFAs) to intravenous infusion of graded doses of isoprenaline was tested. RESULTS: The training did not induce significant weight loss and promoted an increase in maximum aerobic capacity (P |
| Databáze: | OpenAIRE |
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