Recent Advances in Combinatorial Chemistry Applied to Development of Anti-HIV Drugs
| Autor: | Imma Clotet-Codina, José I. Borrell, José A. Esté, Sofia Pettersson, Jordi Teixidó |
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| Rok vydání: | 2006 |
| Předmět: |
Pharmacology
Molecular Structure Combinatorial Chemistry Techniques Anti-HIV Agents Computer science HIV virus diseases HIV Protease Inhibitors General Medicine Computational biology Drug development HIV Fusion Inhibitors Drug Discovery High-Throughput Screening Assays Anti-hiv drugs Humans Reverse Transcriptase Inhibitors HIV Integrase Inhibitors |
| Zdroj: | Mini-Reviews in Medicinal Chemistry. 6:91-108 |
| ISSN: | 1389-5575 |
| Popis: | A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with high throughput screening assays has allowed the discovery and optimization of novel lead anti-HIV compounds. |
| Databáze: | OpenAIRE |
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