Synthesis and Biological Evaluation of 1,2,4-Triazole Thioethers as Both Potential Virulence Factor Inhibitors against Plant Bacterial Diseases and Agricultural Antiviral Agents against Tobacco Mosaic Virus Infections

Autor:	Wu-Bin Shao, Pei-Yi Wang, Zi-Mian Fang, Jin-Jing Wang, Deng-Xuan Guo, Jin Ji, Xiang Zhou, Pu-Ying Qi, Li-Wei Liu, Song Yang
Rok vydání:	2021
Předmět:	Xanthomonas Virulence Factors Oryza Bacterial Infections Microbial Sensitivity Tests General Chemistry Sulfides Triazoles Antiviral Agents Anti-Bacterial Agents Tobacco Mosaic Virus Humans General Agricultural and Biological Sciences Plant Diseases
Zdroj:	Journal of Agricultural and Food Chemistry. 69:15108-15122
ISSN:	1520-5118 0021-8561
Popis:	Targeting the virulence factors of phytopathogenic bacteria is an innovative strategy for alleviating or eliminating the pathogenicity and rapid outbreak of plant microbial diseases. Therefore, several types of 1,2,4-triazole thioethers bearing an amide linkage were prepared and screened to develop virulence factor inhibitors. Besides, the 1,2,4-triazole scaffold was exchanged by a versatile 1,3,4-oxadiazole core to expand molecular diversity. Bioassay results revealed that a 1,2,4-triazole thioether
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67635ee3cdffcf78f4a029645af73e12 https://doi.org/10.1021/acs.jafc.1c05202 Zobrazit plný text záznamu