Energy compensation and adiposity in humans
| Autor: | Jacob Plange-Rhule, Hiroyuki Sagayama, Yosuke Yamada, Lara R. Dugas, Ellen E. Blaak, Cornelia U Loechl, Sumei Hu, Stephane Blanc, Sai Krupa Das, John J. Reilly, Samuel S. Urlacher, Issad Baddou, Ross L. Prentice, Kirsi H. Pietiläinen, Brian M. Wood, Guy Plasqui, Kweku Bedu-Addo, William E. Kraus, Asmaa El Hamdouchi, Nancy F. Butte, Catherine Hambly, Roberto A Rabinovich, Dale A. Schoeller, Erwin P. Meijer, James C Morehen, Vincent Careau, Noorjehan Joonas, Marije B. Hoos, Philip N. Ainslie, Jennifer Rood, Terrence Forrester, James P. Morton, Simon D. Eaton, Alberto G. Bonomi, William W. Wong, William R. Leonard, Graeme L. Close, Jonathan C. K. Wells, Lene Frost Andersen, Robert Ojiambo, Annelies H. C. Goris, Barry W. Fudge, Lewis G. Halsey, Peter T. Katzmarzyk, Lenore Arab, Misaka Kimura, George S. Wilson, Robert F. Kushner, Xueying Zhang, Albertine J. Schuit, Susan B. Racette, Kitty P. Kempen, Giulio Valenti, Amy Luke, Nader Lessan, Ulf Ekelund, Annemiek M. C. P. Joosen, Anders Sjödin, Susan B. Roberts, Anine Christine Medin, Marian L. Neuhouser, Eric Ravussin, Maciej S. Buchowski, Yannis P. Pitsiladis, Michael Gurven, David A. Raichlen, Edgar A. Van Mil, Jack A. Yanovski, Liam J. Anderson, Tsukasa Yoshida, Corby K. Martin, Jamie A. Cooper, Stefan G J A Camps, John R. Speakman, Richard Cooper, Rebecca M. Reynolds, Alexia J. Murphy-Alford, Ludo M. Van Etten, Carlijn V. C. Bouten, Estelle V. Lambert, Eric Stice, Theresa A. Nicklas, Herman Pontzer, Sonja Entringer |
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| Přispěvatelé: | Cell-Matrix Interact. Cardiov. Tissue Reg., ICMS Core, HUS Abdominal Center, Department of Medicine, Clinicum, Research Programs Unit, CAMM - Research Program for Clinical and Molecular Metabolism, Executive Board, Humane Biologie, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, Nutrition and Movement Sciences, RS: NUTRIM - R3 - Respiratory & Age-related Health, FSE Campus Venlo, RS: FSE UCV |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Calorie
030309 nutrition & dietetics Energy balance RA773 SDG 3 – Goede gezondheid en welzijn Cardiovascular Medical and Health Sciences Oral and gastrointestinal Compensation (engineering) RC1200 0302 clinical medicine Weight loss energy compensation Adiposity Cancer 0303 health sciences exercise CONSTRAINT Biological Sciences Stroke IAEA DLW database group EXERCISE PHYSICAL-ACTIVITY medicine.symptom General Agricultural and Biological Sciences INTERVENTIONS Energy (esotericism) WEIGHT-LOSS 030209 endocrinology & metabolism MASS Biology Article General Biochemistry Genetics and Molecular Biology 03 medical and health sciences Affordable and Clean Energy SDG 3 - Good Health and Well-being Total energy expenditure Clinical Research daily energy expenditure medicine VDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470 Humans BASAL Obesity Metabolic and endocrine energy management models Nutrition Homo sapiens BIRDS activity Psychology and Cognitive Sciences medicine.disease trade-offs METABOLIC-RATES Basal metabolic rate basal metabolic rate 1182 Biochemistry cell and molecular biology Demographic economics 3111 Biomedicine weight loss Energy Metabolism Energy Intake EXPENDITURE Developmental Biology |
| Zdroj: | Current Biology 4659–4666 Current Biology, 31(20), 4659-4666.e2. Cell Press Current biology : CB, vol 31, iss 20 Current Biology, 31(20), 4659-4666. Cell Press Halsey, L G, Pontzer, H, Ainslie, P N, Andersen, L F, Anderson, L J, Arab, L, Sjödin, A M, Luke, A H, Rood, J, Sagayama, H, Schoeller, D A, Wong, W W, Yamada, Y, Speakman, J R & IAEA DLW database group 2021, ' Energy compensation and adiposity in humans ', Current Biology, vol. 31, no. 20, pp. 4659-4666.e2 . https://doi.org/10.1016/j.cub.2021.08.016 Curr Biol |
| ISSN: | 0960-9822 1879-0445 |
| Popis: | Publisher Copyright: © 2021 The Authors Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1–3 This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response—energy compensation. We used the largest dataset compiled on adult TEE and basal energy expenditure (BEE) (n = 1,754) of people living normal lives to find that energy compensation by a typical human averages 28% due to reduced BEE; this suggests that only 72% of the extra calories we burn from additional activity translates into extra calories burned that day. Moreover, the degree of energy compensation varied considerably between people of different body compositions. This association between compensation and adiposity could be due to among-individual differences in compensation: people who compensate more may be more likely to accumulate body fat. Alternatively, the process might occur within individuals: as we get fatter, our body might compensate more strongly for the calories burned during activity, making losing fat progressively more difficult. Determining the causality of the relationship between energy compensation and adiposity will be key to improving public health strategies regarding obesity. |
| Databáze: | OpenAIRE |
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