Work productivity among Sjögren’s Syndrome and non-Sjögren’s dry eye patients: a systematic review and meta-analysis

Autor: Rookaya Mather, Monali S. Malvankar-Mehta, Janhavi Patel, Gayathri K Sivakumar
Rok vydání: 2021
Předmět:
Zdroj: Eye (Lond)
ISSN: 1476-5454
0950-222X
DOI: 10.1038/s41433-020-01282-3
Popis: Background Dry eye disease (DED) is one of the most common conditions presenting to eye care providers and is increasingly recognized to have poor outcomes on quality of life, activities of daily living, and social and emotional well-being. Here, we aim to understand the association between dry eye symptoms and workplace productivity experienced by patients with non-Sjogren's dry eye and Sjogren's Syndrome. Methods MEDLINE, PubMed, Embase, Cochrane Library, CINAHL, Healthstar, and PsycINFO were searched from inception to May 2019. Results Thirty-one studies consisting of 50,446 study participants from 14 countries were included in this systematic review. Among non-Sjogren's dry eye patients, there was significant absenteeism (ES = 0.19; 95% CI: [0.04, 0.35]), presenteeism (ES = 0.25; 95% CI: [0.15. 0.35]), productivity impairment (ES = 0.24; 95% CI: [0.20, 0.27]), activity impairment (ES = 0.30; 95% CI: [0.21, 0.38]), and subjective difficulties at work (ES = 0.58; 95% CI: [0.40, 0.75]). Patients with Sjogren's Syndrome demonstrated significant absenteeism (ES = 0.13, 95% CI: [0.10, 0.17]), presenteeism (ES = 0.28, 95% CI: [0.24, 0.32]), productivity impairment (ES = 0.31, 95% CI: [0.27, 0.35]), and activity impairment (ES = 0.39, 95% CI: [0.32, 0.47]) in the workplace. In addition, patients with Sjogren's Syndrome demonstrated significantly lower employment rate (ES = 0.42, 95% CI: [0.34, 0.50]), decreased number of hours worked (SMD = -0.21, 95% CI: [-0.39, -0.02]), and increased work disability (ES = 0.18; 95% CI: [0.09, 0.27]). Conclusions This is the first systematic review and meta-analysis to demonstrate the negative association between DED and several work productivity measures.
Databáze: OpenAIRE