A pilot study of normative data for macular thickness and volume measurements using cirrus high-definition optical coherence tomography
| Autor: | Steven D. Schwartz, Fei Yu, Andrew Kaines, Allen Y.H. Hu, Jean-Pierre Hubschman, Tiffany Liu |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Aging genetic structures Visual Acuity Pilot Projects Retina Diabetes Complications Young Adult Optics Sex Factors Optical coherence tomography Sex factors Reference Values Ophthalmology medicine Humans Intraocular Pressure Aged Retrospective Studies Aged 80 and over medicine.diagnostic_test business.industry General Medicine Middle Aged eye diseases Volume measurements Reference values High definition Normative Cirrus Female sense organs Tomography business Tomography Optical Coherence |
| Zdroj: | Retina (Philadelphia, Pa.). 31(9) |
| ISSN: | 1539-2864 |
| Popis: | To establish preliminary normative data for macular thickness (MT) and macular volume (MV) by Cirrus high-definition optical coherence tomography (Carl Zeiss Meditec, Dublin, CA).Retrospective case series of 192 eyes of 192 subjects (age, 20-90 years) without retinal disease or surgery with best-corrected visual acuity ≥ 20/25, intraocular pressure21 mmHg, and cup-to-disc ratio ≤ 0.5 were enrolled. Retinal thicknesses in nine Early Treatment Diabetic Retinopathy Study subfields (including central subfield thickness [CST]), MT, and MV were measured with Cirrus high-definition optical coherence tomography. Effects of age, gender, lens status, and diabetic status on these measurements were analyzed.The mean ± SD CST, MT, and MV were 262.4 ± 22.8 μm, 281.3 ± 14.5 μm, and 10.1 ± 0.6 mm3, respectively. Although CST and age were not associated (P = 0.45), both mean MT and mean MV declined with age (P0.0001). Central subfield thickness (P = 0.002), mean MT (P = 0.021), and MV (P = 0.041) were higher in men compared with women. Neither lens status nor diabetic status affected CST, MT, or MV.A pilot study showed that preliminary normative CST, MT, and MV values were obtained by Cirrus high-definition optical coherence tomography. The authors propose that CST ranges from 216.8 μm to 308 μm in normal eyes. Older age and female gender were associated with thinner MT. |
| Databáze: | OpenAIRE |
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