Sonographic features of primary ovarian fibrosarcoma: a report of two cases
| Autor: | A. Licameli, Giovanni Scambia, Antonia Carla Testa, Floriana Mascilini, Adrius Gaurilčikas, M. Malaggese, A. Di Legge, R. Mancari, Gabriella Ferrandina, Gian Franco Zannoni |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Pathology medicine.medical_specialty ovarian fibrosarcoma Fibrosarcoma Ovary Fibroma Lesion Diagnosis Differential medicine Humans Radiology Nuclear Medicine and imaging Nuclear atypia Ultrasonography Ovarian Neoplasms Radiological and Ultrasound Technology ultrasound business.industry Obstetrics and Gynecology General Medicine Ovarian Fibrosarcoma Middle Aged medicine.disease stomatognathic diseases Settore MED/40 - GINECOLOGIA E OSTETRICIA medicine.anatomical_structure Reproductive Medicine Female Sarcoma Differential diagnosis medicine.symptom business |
| Zdroj: | Ultrasound in obstetricsgynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 33(1) |
| ISSN: | 1469-0705 |
| Popis: | Two cases of primary cellular fibroblastic tumor of the ovary are described, which presented a challenging clinical and histopathological differential diagnosis of primary ovarian fibrosarcoma and mitotically active cellular fibroma. On sonographic evaluation they both appeared as solid lesions with irregular margins, and on histological analysis both showed a count of 5-7 mitotic figures per 10 high-power fields. Histopathological examination of the first case was characterized by the presence of hemorrhage, necrosis and severe nuclear atypia, with a metastatic peritoneal lesion, and the eventual diagnosis was primary ovarian fibrosarcoma. The second case, however, was diagnosed as a 'mitotically active cellular fibroma' owing to the lack of substantial severe cellular atypia, hemorrhage or necrosis. We speculate that ovarian fibrosarcoma at the preoperative examination might be considered in the differential diagnosis whenever a unilateral, heterogeneous, largely round solid ovarian lesion is detected. |
| Databáze: | OpenAIRE |
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