Lidocaine 700 mg medicated plaster for postherpetic neuralgia: real-world data from the German Pain e-Registry
| Autor: | Ingo Sabatschus, Mariëlle Eerdekens, Els Hollanders, Michael A. Überall, Irmgard Bösl |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Lidocaine Postherpetic neuralgia business.industry Neuralgia Postherpetic Retrospective cohort study General Medicine medicine.disease Discontinuation Tolerability Internal medicine Neuropathic pain Propensity score matching medicine Quality of Life Humans Registries Anesthetics Local Adverse effect business medicine.drug Retrospective Studies |
| Zdroj: | Pain management. 12(2) |
| ISSN: | 1758-1877 |
| Popis: | Aim: To provide real-world evidence for the effectiveness and tolerability of lidocaine 700 mg medicated plaster (LMP) compared with oral systemic first-line medications (OSM) in postherpetic neuralgia treatment. Patients & methods: Retrospective cohort study in patients refractory to at least one recommended OSM (single drug or a combination of drugs) using anonymized routine medical care data from the German Pain e-Registry. A matched pair approach using propensity score matching was employed. Results: A total of 1711 data sets of postherpetic neuralgia patients were identified per treatment group. The majority (>60%) had experienced pain for more than a year and reported a high burden of pain and reduced quality of life. Six months of LMP treatment provided significantly greater pain reductions, improvements in pain-related impairments and quality of life than OSM treatment (p |
| Databáze: | OpenAIRE |
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