Impact of histological chorioamnionitis on postnatal growth in very-low birth weight infants
| Autor: | Montserrat Izquierdo Renau, Elsa García González, Isabel Iglesias Platas, Alba Vergès Castells, Victoria Aldecoa-Bilbao, Carlota Rovira Zurriaga |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Placenta Gestational Age Chorioamnionitis Cohort Studies 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics medicine Birth Weight Humans Postnatal growth Retrospective Studies 030219 obstetrics & reproductive medicine Obstetrics business.industry Infant Newborn Infant Obstetrics and Gynecology medicine.disease Very preterm Low birth weight Pediatrics Perinatology and Child Health Female medicine.symptom business Infant Premature |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 34:1780-1785 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.1080/14767058.2019.1648423 |
| Popis: | Postnatal growth restriction remains one of the most common problems of very preterm infants (VPI). Chorioamnionitis is a frequent cause of prematurity. Both have been related to worse postnatal outcomes.To evaluate the influence of histological chorioamnionitis (CA) on postnatal growth in very premature infants.Retrospective one-to-one matched cohort study assessing growth in infants born at or below 32.0 weeks gestation from mothers for whom histological examination of the placenta was available. Newborns with histological CA were matched and compared with those without it. Postnatal growth was recorded at admission, 14 days of life, 28 days of life and 36 weeks postmenstrual age (PMA). Nutritional support and clinical outcomes were used as covariables.Eighty-eight patients were included: 44 with fetal or/and maternal placental inflammation, and 44 without histological CA (41% with vasculopathy findings and 59% without). Baseline characteristics were similar between the groups. Change in weight z-scores at 14 days of life, 28 days of life, 36 weeks PMA or at discharge were similar in both groups, with a steady fall and no signs of catch-up. No differences were found in enteral and parenteral nutritional intakes between groups.Histological CA did not affect postnatal growth of very preterm infants after matching for birth weight z-scores with non-CA newborns. |
| Databáze: | OpenAIRE |
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