Using Both Sides of Your Brain: The Case for Rapid Interhemispheric Switching
| Autor: | Georg B. Keller, Claude Z.-H. Wang, Richard H. R. Hahnloser, Joshua A. Herbst |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Male
Models Anatomic Sound Spectrography animal structures High Vocal Center QH301-705.5 Stimulation Hindbrain General Biochemistry Genetics and Molecular Biology Lateralization of brain function Functional Laterality medicine Functional electrical stimulation Animals Biology (General) Zebra finch General Immunology and Microbiology biology Cerebrum General Neuroscience Brain Anatomy biology.organism_classification Vocal production Songbird medicine.anatomical_structure nervous system Finches Vocalization Animal General Agricultural and Biological Sciences Neuroscience psychological phenomena and processes Research Article |
| Zdroj: | PLoS Biology, 6 (10) PLoS Biology, Vol 6, Iss 10, p e250 (2008) PLoS Biology |
| ISSN: | 1544-9173 1545-7885 |
| Popis: | To generate complex bilateral motor patterns such as those underlying birdsong, neural activity must be highly coordinated across the two cerebral hemispheres. However, it remains largely elusive how this coordination is achieved given that interhemispheric communication between song-control areas in the avian cerebrum is restricted to projections received from bilaterally connecting areas in the mid- and hindbrain. By electrically stimulating cerebral premotor areas in zebra finches, we find that behavioral effectiveness of stimulation rapidly switches between hemispheres. In time intervals in which stimulation in one hemisphere tends to distort songs, stimulation in the other hemisphere is mostly ineffective, revealing an idiosyncratic form of motor dominance that bounces back and forth between hemispheres like a virtual ping-pong ball. The intervals of lateralized effectiveness are broadly distributed and are unrelated to simple spectral and temporal song features. Such interhemispheric switching could be an important dynamical aspect of neural coordination that may have evolved from simpler pattern generator circuits. PLoS Biology, 6 (10) ISSN:1544-9173 ISSN:1545-7885 |
| Databáze: | OpenAIRE |
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