Prevalence and severity of malnutrition in hospitalized COVID-19 patients

Autor: Pauline Faucher, Zahir Amoura, C. Ciangura, Christine Poitou-Bernert, Jehane Fadlallah, Jean-Michel Oppert, Héléna Mosbah, Pierre Bel Lassen, Alexis Mathian, Pauline Moreau, Anne-Caroline Jeannin, Dorothée Bedock, Julie Couffignal
Přispěvatelé: Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Centre d'Immunologie et de Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CCSD, Accord Elsevier, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Nutrition et obésités: approches systémiques (UMR-S 1269) (Nutriomics), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut E3M [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
0301 basic medicine
Male
Pediatrics
Endocrinology
Diabetes and Metabolism
[SDV]Life Sciences [q-bio]
Logistic regression
Severity of Illness Index
law.invention
0302 clinical medicine
law
Nutritional knowledge
SARS-Cov2
Prevalence
Medicine
Hospital Mortality
Longitudinal Studies
2. Zero hunger
Nutrition and Dietetics
Middle Aged
University hospital
Intensive care unit
3. Good health
Hospitalization
[SDV] Life Sciences [q-bio]
Female
Original Article
France
Coronavirus Infections
Adult
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Pneumonia
Viral
030209 endocrinology & metabolism
03 medical and health sciences
Betacoronavirus
Disease severity
Humans
In patient
Pandemics
Aged
030109 nutrition & dietetics
business.industry
SARS-CoV-2
Albumin
Malnutrition
COVID-19
Pneumonia
medicine.disease
Nutrition Assessment
business
Zdroj: Clinical Nutrition ESPEN
Clinical Nutrition ESPEN, ESPEN/Elsevier, 2020, 40, pp.214-219. ⟨10.1016/j.clnesp.2020.09.018⟩
Clinical Nutrition ESPEN, 2020, 40, pp.214-219. ⟨10.1016/j.clnesp.2020.09.018⟩
Clinical Nutrition Espen
ISSN: 2405-4577
DOI: 10.1016/j.clnesp.2020.09.018⟩
Popis: International audience; Background & aims: Nutritional knowledge in patients with SARS-Cov2 infection (COVID-19) is limited. Our objectives were: i) to assess malnutrition in hospitalized COVID-19 patients, ii) to investigate the links between malnutrition and disease severity at admission, iii) to study the impact of malnutrition on clinical outcomes such as transfer to an intensive care unit (ICU) or death.Methods: Consecutive patients hospitalized in a medicine ward at a university hospital were included from March 21st to April 24th 2020 (n = 114, 60.5% males, age: 59.9 ± 15.9 years). Nutritional status was defined using Global Leadership Initiative on Malnutrition (GLIM) criteria. Clinical, radiological and biological characteristics of COVID-19 patients were compared according to the presence of malnutrition. Logistic regression was used to assess associations between nutritional parameters and unfavourable outcomes such as transfer to intensive care unit (ICU) or death.Results: The overall prevalence of malnutrition was 42.1% (moderate: 23.7%, severe: 18.4%). The prevalence of malnutrition reached 66.7% in patients admitted from ICU. No significant association was found between nutritional status and clinical signs of COVID-19. Lower albumin levels were associated with a higher risk of transfer to ICU (for 10 g/l of albumin, OR [95%CI]: 0.31 [0.1; 0.7]; p < 0.01) and this association was independent of age and CRP levels.Conclusions: COVID-19 in medical units dedicated to non-intensive care is associated with a high prevalence of malnutrition, especially for patients transferred from ICU. These data emphasize the importance of early nutritional screening in these patients to adapt management accordingly.
Databáze: OpenAIRE
Externí odkaz: