Possible serotonin syndrome with carbidopa-levodopa and linezolid
| Autor: | Natasha N Pettit, Emeka Anyanwu, V. Alonso, E. Wojcik, L. Ebara, J.-L. Benoit |
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| Rok vydání: | 2016 |
| Předmět: |
Serotonin Syndrome
030506 rehabilitation Levodopa Serotonergic Serotonin syndrome Carbidopa/levodopa 03 medical and health sciences chemistry.chemical_compound Serotonin Agents 0302 clinical medicine Humans Medicine Drug Interactions heterocyclic compounds Pharmacology (medical) 030212 general & internal medicine Aged 80 and over Pharmacology business.industry organic chemicals Linezolid Carbidopa biochemical phenomena metabolism and nutrition bacterial infections and mycoses Anti-Bacterial Agents Discontinuation Drug Combinations chemistry Anesthesia Dopamine Agonists bacteria Female medicine.symptom 0305 other medical science business medicine.drug |
| Zdroj: | Journal of Clinical Pharmacy and Therapeutics. 41:101-103 |
| ISSN: | 0269-4727 |
| DOI: | 10.1111/jcpt.12352 |
| Popis: | SummaryWhat is known and objective Serotonin syndrome (SS) can occur when linezolid is combined with other serotonergic agents. Case description We report a case of possible SS in an elderly patient receiving linezolid in combination with carbidopa–levodopa (CL). What is new and conclusion Although certain classes of agents are commonly reported as causing SS among patients receiving linezolid, there are no specific case reports detailing this reaction with CL. Linezolid combined with CL should generally be avoided; however, if linezolid must be used, discontinuation of other agents with serotonergic activity is recommended with careful monitoring for signs and symptoms of SS. |
| Databáze: | OpenAIRE |
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