FTIR characterization of Sahara honey and propolis and evaluation of its anticandidal potentials
| Autor: | Saad Aissat, Mohamed Amine Aissa, Mokhtar Amirat, Baghdad Khiati, Moussa Ahmed |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Geography (General) 0303 health sciences ftir biology 030306 microbiology Chemistry Science digestive oral and skin physiology 030231 tropical medicine food and beverages honey Propolis biology.organism_classification propolis 03 medical and health sciences 0302 clinical medicine antibiofilm activity G1-922 Organic chemistry candida albicans Pediatrics Perinatology and Child Health Fourier transform infrared spectroscopy Candida albicans |
| Zdroj: | Acta Scientifica Naturalis, Vol 7, Iss 3, Pp 46-57 (2020) |
| ISSN: | 2367-5144 |
| DOI: | 10.2478/asn-2020-0032 |
| Popis: | Antifungal of bee products have been shown to be protective against microbial biofilms invasion Sahara honey and propolis were applied as an antimicrobial in treatment for many infections in Algeria. In this study, Fourier transform infrared spectroscopy (FTIR) analysis was utilized to characterize the chemical structures and functional groups. In addition, in this study, we determined the anti-candida activity of honey used alone or in combination with propolis. Proteins, carbohydrates, carboxylic acids, free amino acids, cellulose and lipids, ketones and phenol compounds were identified by FTIR analysis. Combination of Sahara honey and propolis increased antifungal efficacy, compared to compounds tested alone. Propolis increased the anti-candidal effect of Sahara honey. In addition, the treatment of Sahara honey and Propolis-Sahara honey catheters with a Candida albicans biofilms reduced biofilm formation after 24 and 48-h exposure period. The results provide evidence that honey/propolis combination may help in designing a more potent novel, natural antibiofilm blend at sufficiently low concentrations in medical domain. |
| Databáze: | OpenAIRE |
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