Thymectomy for Nonthymomatous Myasthenia Gravis

Autor: Ali Rahnama, Reza Afghani, Ali Sadrizadeh, Mohammad Baradaran Firoozabadi, Reza Bagheri, Saeed Hakimian, Reza Boonstani, Maryam Salehi, Vahab Azmounfar
Rok vydání: 2018
Předmět:
Zdroj: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 13:77-80
ISSN: 1559-0879
1556-9845
DOI: 10.1097/imi.0000000000000490
Popis: Objective Thymectomy considered as a standard procedure in treatment of all the steps of myasthenia gravis. Video-assisted thoracoscopic surgery (VATS) thymectomy is one of the minimally invasive procedures that because of the short duration of hospitalization, less postoperative pain, and scar after surgery, nowadays it is replaced the traditional methods of surgery for patients with myasthenia gravis, but there are still differences and concerns. The aim of this study was to compare outcomes of two different techniques of surgery, VATS versus transsternal (TS) in the treatment of myasthenia gravis. Methods In this pilot study, 42 patients with myasthenia gravis and without a thymus tumor were evaluated based on Myasthenia Gravis Foundation of America classification and drug consumption. Then, they randomly underwent two different techniques of surgery: VATS versus TS. Patients were evaluated based on preoperative and postoperative variables. Results Duration of intensive care unit stay and hospitalization has been reduced in patients who underwent VATS thymectomy operation technique. In addition, duration of surgical procedure has been reduced significantly in these patients. These patients have less blood loss during surgery compared with TS group. The Myasthenia Gravis Foundation of America postoperative status in VATS thymectomy revealed that the number of patients with complete stable remission was higher and number of persons remained unchanged was lower in this group. Conclusions VATS thymectomy is a safe and appropriate approach comparing with traditional methods such as TS thymectomy for patients with myasthenia gravis. This method has better results after surgery and can be used as a minimally invasive alternative method instead of TS thymectomy.
Databáze: OpenAIRE