Differential diagnosis of coronavirus disease 2019 pneumonia or influenza A pneumonia by clinical characteristics and laboratory findings

Autor: Guoqing Qian, Ding-Feng Lv, Qi-Tian Mu, Bei-Bei Lu, Qi-Ming Ying, Xue-Qin Chen, Jin-Guo Chu, Xing-Bei Weng, Ji-Hong Zhang, Jun Liang, Yi-Wen He
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
0301 basic medicine
Pleural effusion
Clinical Biochemistry
Logistic regression
chemistry.chemical_compound
0302 clinical medicine
Risk Factors
differential diagnosis
Epidemiology
Immunology and Allergy
influenza A
clinical characteristics
Research Articles
Hematology
Middle Aged
Diarrhea
Medical Laboratory Technology
Influenza A virus
030220 oncology & carcinogenesis
Cohort
Female
medicine.symptom
Research Article
Microbiology (medical)
medicine.medical_specialty
Diagnosis
Differential
03 medical and health sciences
COVID‐19
Internal medicine
medicine
Humans
Biochemistry
medical
Creatinine
Clinical Laboratory Techniques
SARS-CoV-2
business.industry
Biochemistry (medical)
Public Health
Environmental and Occupational Health
COVID-19
Pneumonia
medicine.disease
Logistic Models
030104 developmental biology
chemistry
Multivariate Analysis
Differential diagnosis
Tomography
X-Ray Computed
business
Zdroj: Journal of Clinical Laboratory Analysis
ISSN: 1098-2825
0887-8013
DOI: 10.1002/jcla.23685
Popis: Background Pneumonia caused by the 2019 novel Coronavirus (COVID‐2019) shares overlapping signs and symptoms, laboratory findings, imaging features with influenza A pneumonia. We aimed to identify their clinical characteristics to help early diagnosis. Methods We retrospectively retrieved data for laboratory‐confirmed patients admitted with COVID‐19–induced or influenza A–induced pneumonia from electronic medical records in Ningbo First Hospital, China. We recorded patients' epidemiological and clinical features, as well as radiologic and laboratory findings. Results The median age of influenza A cohort was higher and it exhibited higher temperature and higher proportion of pleural effusion. COVID‐19 cohort exhibited higher proportions of fatigue, diarrhea and ground‐glass opacity and higher levels of lymphocyte percentage, absolute lymphocyte count, red‐cell count, hemoglobin and albumin and presented lower levels of monocytes, c‐reactive protein, aspartate aminotransferase, alkaline phosphatase, serum creatinine. Multivariate logistic regression analyses showed that fatigue, ground‐glass opacity, and higher level of albumin were independent risk factors for COVID‐19 pneumonia, while older age, higher temperature, and higher level of monocyte count were independent risk factors for influenza A pneumonia. Conclusions In terms of COVID‐19 pneumonia and influenza A pneumonia, fatigue, ground‐glass opacity, and higher level of albumin tend to be helpful for diagnosis of COVID‐19 pneumonia, while older age, higher temperature, and higher level of monocyte count tend to be helpful for the diagnosis of influenza A pneumonia.
Fatigue, ground‐glass opacity and higher level of albumin tend to be helpful for diagnosis of COVID‐19 pneumonia, while older age, higher temperature, and higher level of monocytes count tend to be helpful for the diagnosis of influenza A pneumonia.
Databáze: OpenAIRE
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