Mitral regurgitation in dilated cardiomyopathy: value of both regional left ventricular contractility and dyssynchrony
| Autor: | Christian de Place, Erwan Donal, Renaud Gervais, Jean-Claude Daubert, Christophe Leclercq, Gaelle Kervio, Fabrice Bauer, Philippe Mabo |
|---|---|
| Přispěvatelé: | Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie et maladies vasculaires [Rennes] = Cardiac, Thoracic, and Vascular Surgery [Rennes], CHU Pontchaillou [Rennes], CIC-IT Rennes, Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de cardiologie [CHU Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Rok vydání: | 2009 |
| Předmět: |
Male
MESH: Mitral Valve Insufficiency MESH: Myocardial Contraction Cardiomyopathy Kaplan-Meier Estimate 030204 cardiovascular system & hematology MESH: Observer Variation MESH: Risk Assessment Severity of Illness Index MESH: Stroke Volume MESH: Ultrasonography Doppler Pulsed MESH: Linear Models 0302 clinical medicine [INFO.INFO-TS]Computer Science [cs]/Signal and Image Processing Mitral valve Prospective Studies 030212 general & internal medicine Observer Variation Myocardial strain imaging Ejection fraction Ventricular Remodeling Mitral Valve Insufficiency MESH: Heart Failure Systolic Dilated cardiomyopathy General Medicine Prognosis MESH: Reproducibility of Results medicine.anatomical_structure Ultrasonography Doppler Pulsed MESH: Survival Analysis cardiovascular system Cardiology Female [SDV.IB]Life Sciences [q-bio]/Bioengineering Cardiology and Cardiovascular Medicine [SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing Cardiomyopathy Dilated medicine.medical_specialty Ventricular dyssynchrony Heart failure MESH: Ventricular Remodeling Risk Assessment MESH: Prognosis MESH: Multivariate Analysis Contractility 03 medical and health sciences [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system MESH: Severity of Illness Index Internal medicine medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases MESH: Cardiomyopathy Dilated MESH: Kaplan-Meier Estimate Mitral regurgitation MESH: Humans business.industry Reproducibility of Results Stroke Volume medicine.disease Myocardial Contraction Survival Analysis MESH: Prospective Studies MESH: Male Ventricle Multivariate Analysis Linear Models Feasibility Studies MESH: Feasibility Studies business MESH: Female Heart Failure Systolic |
| Zdroj: | European Journal of Echocardiography European Journal of Echocardiography, Oxford University Press (OUP), 2009, 10 (1), pp.133-8. ⟨10.1093/ejechocard/jen188⟩ European Journal of Echocardiography, 2009, 10 (1), pp.133-8. ⟨10.1093/ejechocard/jen188⟩ |
| ISSN: | 1532-2114 1525-2167 |
| DOI: | 10.1093/ejechocard/jen188 |
| Popis: | International audience; AIMS: Mitral regurgitation (MR) is common and independently predicts mortality in patients with left ventricular (LV) systolic dysfunction. Its management remains challenging because of the complexity and variety of potential mechanisms implicated. We sought to determine which LV functional characteristics are the most important determinants of the severity of the MR associated with dilated cardiomyopathies. METHODS AND RESULTS: We performed echocardiographic studies in 87 consecutive patients with dilated cardiomyopathy. The degree of MR was quantified according to guidelines. LV, left atrial and mitral annulus dimensions, mitral valve tenting, estimated filling pressures, regional myocardial contractility, and dyssynchrony (using regional strain (epsilon) analysis) were recorded too. Determinants of significant MR was thus assessed using multivariate models. Mitral regurgitant volume correlated with mitral annulus diameter (P |
| Databáze: | OpenAIRE |
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