Submicrometer Metallic Barcodes
| Autor: | Lin He, Michael J. Natan, Christine D. Keating, Brian D. Reiss, R. Griffith Freeman, Sheila R. Nicewarner-Peña, David J. Peña, Remy Cromer, Ian D. Walton |
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| Rok vydání: | 2001 |
| Předmět: |
Optics and Photonics
Materials science Metal ions in aqueous solution Fluorescent Antibody Technique Nanotechnology Electrochemistry Biochemistry Chemistry Techniques Analytical Fluorescence Metal Microscopy Miniaturization Animals Humans Deposition (law) Immunoassay Multidisciplinary Nucleic Acid Hybridization food and beverages Templates Genetic Template Metals Immunoglobulin G visual_art embryonic structures visual_art.visual_art_medium Rabbits Oligonucleotide Probes |
| Zdroj: | Science. 294:137-141 |
| ISSN: | 1095-9203 0036-8075 |
| DOI: | 10.1126/science.294.5540.137 |
| Popis: | We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays. |
| Databáze: | OpenAIRE |
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