Prevalence, Risk Factors, and Clinical Relevance of Fluoroquinolone-Resistant Organisms in Rectal Cultures: Should We Target Antibiotic Prophylaxis Prior to Prostate Biopsy?
| Autor: | J. Van Besien, A. M. Van den Abeele, Luc Merckx, Pieter Uvin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Prostate biopsy medicine.drug_class Urology Antibiotics 030232 urology & nephrology MEDLINE Rectum Review Article lcsh:RC870-923 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Clinical significance In patient Antibiotic prophylaxis medicine.diagnostic_test business.industry Confounding Obstetrics and Gynecology lcsh:Diseases of the genitourinary system. Urology Surgery medicine.anatomical_structure 030220 oncology & carcinogenesis business |
| Zdroj: | Advances in Urology, Vol 2016 (2016) Advances in Urology |
| ISSN: | 1687-6377 1687-6369 |
| Popis: | The rise of infectious complications after prostate biopsy has been linked to the growing resistance of enterobacteria to fluoroquinolone (FQ) antibiotics. In this review, we investigated the potential benefit of targeted antibiotic prophylaxis based on rectal cultures prior to prostate biopsy. An electronic search for all related literature published in English was performed from April until June 2015 using the MEDLINE and EMBASE databases. Data were obtained regarding the true prevalence of FQ-resistant bacteria in the rectum of patients, the identification of those patients at risk of harbouring FQ-resistant bacteria, the risk of infectious complications after transrectal prostate biopsy in patients with FQ-resistant bacteria, and the effect of targeted prophylaxis. Although there is limited evidence that a targeted approach might be beneficial, we conclude that current studies on the use of rectal cultures in the prebiopsy setting have too many limitations and confounding variables to definitely accept this approach in clinical practice. Whether this methodology is useful in a certain region will greatly depend on local fluoroquinolone-resistance rates. |
| Databáze: | OpenAIRE |
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