Surgical Site Infections Complicating the Use of Negative Pressure Wound Therapy in Renal Transplant Recipients

Autor:	Deborah Verran, Susanna Lam, Ngee-Soon Lau, Jerome M. Laurence
Rok vydání:	2019
Předmět:	medicine.medical_specialty Debridement business.industry Wound dehiscence medicine.medical_treatment lcsh:Surgery Case Report lcsh:RD1-811 030230 surgery medicine.disease Surgery Sepsis Abdominal wall Bioburden 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Renal transplant 030220 oncology & carcinogenesis Management of Technology and Innovation Negative-pressure wound therapy medicine business Complication
Zdroj:	Case Reports in Transplantation Case Reports in Transplantation, Vol 2019 (2019)
ISSN:	2090-6951 2090-6943
DOI:	10.1155/2019/2452857
Popis:	Surgical site infections (SSI) of the abdominal wall in renal transplant recipients can on occasion require management with negative pressure wound therapy (NPWT). This is often successful, with a low risk of further complications. However, we describe three cases in which persistent or recurrent surgical site sepsis occurred, whilst NPWT was being deployed in adults with either wound dehiscence or initial SSI. This type of complication in the setting of NPWT has not been previously described in renal transplant recipients. Our case series demonstrates that in immunosuppressed transplant recipients, there may be ineffective microbial or bacterial bioburden clearance associated with the NPWT, which can lead to further infections. Hence recognition for infections in renal transplant patients undergoing treatment with NPWT is vital; furthermore, aggressive management of sepsis control with early debridement, antimicrobial use, and reassessment of the use of wound dressing is necessary to reduce the morbidity associated with surgical site infections and NPWT.
Databáze:	OpenAIRE
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