HIV-1 seroprevalence among childbearing women in northern Thailand: monitoring a rapidly evolving epidemic
| Autor: | Somboonsak Yanpaisarn, Philip Rhodes, Khanchit Limpakarnjanarat, Peter H. Kilmarx, M E St Louis, Timothy D. Mastro, Renu Srismith, Rebecca Bunnell |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Immunology Population HIV Infections Disease Outbreaks Acquired immunodeficiency syndrome (AIDS) Pregnancy Epidemiology Prevalence Immunology and Allergy Medicine Seroprevalence Humans Pregnancy Complications Infectious Sida education education.field_of_study biology business.industry Public health Infant Newborn medicine.disease biology.organism_classification Thailand Confidence interval Infectious Diseases Multivariate Analysis HIV-1 Female business Demography |
| Zdroj: | AIDS (London, England). 13(4) |
| ISSN: | 0269-9370 |
| Popis: | The objectives were to describe trends in prevalence of HIV-1 infection among women giving birth at Chiang Rai Hospital (CRH) and to assess risk factors associated with HIV infection in this population. Analysis of hospital registry data for all deliveries at CRH from 1990 to mid-1997 was carried out. From 1990 to mid- 1997 women giving birth at CRH were tested for HIV-1 infection using enzyme immunoassay (EIA); positive sera were confirmed using a different manufacturers EIA. Demographic and clinical data were abstracted from delivery-ward log books. Data from 40723 deliveries indicated that overall HIV-1 seroprevalence increased sharply from 1.3% in 1990 to a peak of 6.4% in 1994 and then declined to 4.6% in the first 6 months of 1997. Prevalence was highest at 7.0% among young (age 24 or younger) primigravidas compared with 2.4% among older (age 25 or older) multigravidas. When the authors controlled for age prevalence declined 40% during 1994-97 among young primigravidas (95% confidence interval for percentage reduction 16-57). Among older multigravid women prevalence was consistently lower but increased steadily from 2.7% in 1994 to 3.4% in 1997. A rapid rise in HIV prevalence in childbearing women was followed by a sharp decline among young primigravidas. In each year the prevalence was highest among young primigravidas. They may be the best subgroup of pregnant women for monitoring HIV epidemic trends but they also represent a challenging prevention priority that will require its own targeted interventions. (authors) |
| Databáze: | OpenAIRE |
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