Oligonucleotide-stabilized Ag nanocluster fluorophores
| Autor: | Yih-Ling Tzeng, Christopher I. Richards, Yasuko Antoku, Robert M. Dickson, Angelo Bongiorno, Sungmoon Choi, Tom Vosch, Jung-Cheng Hsiang |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Silver
Oligonucleotide Photochemistry Kinetics Oligonucleotides Nanotechnology General Chemistry DNA Single-molecule experiment Biochemistry Fluorescence Catalysis Article Nanoclusters Nanostructures chemistry.chemical_compound Colloid and Surface Chemistry chemistry Quantum dot Cyanine Spectroscopy Fluorescent Dyes Oligonucleotide Array Sequence Analysis |
| Zdroj: | Journal of the American Chemical Society. 130(15) |
| ISSN: | 1520-5126 |
| Popis: | Single-stranded oligonucleotides stabilize highly fluorescent Ag nanoclusters, with emission colors tunable via DNA sequence. We utilized DNA microarrays to optimize these scaffold sequences for creating nearly spectrally pure Ag nanocluster fluorophores that are highly photostable and exhibit great buffer stability. Five different nanocluster emitters have been created with tunable emission from the blue to the near-IR and excellent photophysical properties. Ensemble and single molecule fluorescence studies show that oligonucleotide encapsulated Ag nanoclusters exhibit significantly greater photostability and higher emission rates than commonly used cyanine dyes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|