Mosquito-borne viruses circulating in Kinshasa, Democratic Republic of the Congo
| Autor: | Josue Zanga, Fortunate Shija, Roger Wumba, Thierry Lengu Bobanga, Michel Ntetani Aloni, Kennedy Makola Mbanzulu, Gerald Misinzo, Jean Pierre Kambala Mukendi |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Veterinary medicine medicine.medical_specialty Kinshasa Orthobunyavirus viruses 030231 tropical medicine Alphavirus medicine.disease_cause Mosquitoes Arbovirus Article lcsh:Infectious and parasitic diseases 03 medical and health sciences 0302 clinical medicine parasitic diseases medicine Animals Humans lcsh:RC109-216 Chikungunya Rift Valley fever biology business.industry Flavivirus Public health fungi virus diseases General Medicine Mosquito-borne viruses medicine.disease biology.organism_classification Virology humanities 3. Good health Cross-Sectional Studies Culicidae 030104 developmental biology Infectious Diseases Africa Democratic Republic of the Congo Female Livestock Bunyaviridae business Arboviruses |
| Zdroj: | International Journal of Infectious Diseases International Journal of Infectious Diseases, Vol 57, Iss C, Pp 32-37 (2017) |
| ISSN: | 1201-9712 |
| DOI: | 10.1016/j.ijid.2017.01.016 |
| Popis: | Highlights • Adult mosquitoes collected in Kinshasa, the Democratic Republic of the Congo (DRC), were screened for viruses in this study. • Approximately 40% of mosquitoes were found to be infected with Alphavirus, Flavivirus, and/or Bunyaviridae. • Chikungunya, o’nyong’nyong, and Rift valley fever viruses were found in mosquitoes. • Habitats favouring mosquito breeding and viral transmission were found in Kinshasa. • Screening for mosquito-borne viruses in humans and livestock in DRC is recommended. Summary Background Diseases caused by mosquito-borne viruses are among the most important emerging diseases that threaten human and animal health, particularly in Africa. However, little attention has been paid to these diseases in the Democratic Republic of the Congo (DRC). The present cross-sectional study was undertaken between March and May 2014 to investigate the presence of mosquito-borne viruses in mosquitoes collected from five municipalities of Kinshasa, DRC. Methods Mosquitoes were collected using BG-Sentinel traps and battery-powered aspirators. Female mosquitoes were pooled according to their genera and sampling locations, preserved in RNAlater, and later screened for viruses using reverse transcription PCR (RT-PCR) assays. Results A total of 2922 mosquitoes were collected and 29 pools of female mosquitoes, containing approximately 30 mosquitoes each, were tested. Twelve of the 29 (41.4%) mosquito pools were found to be infected with at least one arbovirus, with eight (27.5%) pools positive for Alphavirus, nine (31%) for Flavivirus, and five (17.2%) for Bunyaviridae. Chikungunya, o’nyong’nyong, and Rift valley fever viruses were detected. Conclusions The present study shows that mosquitoes in Kinshasa carry mosquito-borne viruses that may have serious public health implications. Further investigations on the presence of mosquito-borne viruses in the human and livestock populations of Kinshasa and DRC are recommended. |
| Databáze: | OpenAIRE |
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