Comparative Transcriptomes of the Body Wall of Wild and Farmed Sea Cucumber Isostichopus badionotus
| Autor: | Cristobal Garikoitz-Legarda, Alicia Poot-Salazar, Víctor May-Solis, Jesús Alejandro Zamora-Briseño, Juan Antonio Pérez-Vega, Alberto Dávalos, Juan Carlos Triviño, George Grant, Leticia Olivera-Castillo, Nuvia Kantún-Moreno, Roberto Martín-Hernández, Judit Gil-Zamorano, Rossanna Rodríguez-Canul, Oscar Medina-Contreras, Miguel A. Olvera-Novoa |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Sea Cucumbers RNA-sequencing Zoology Animals Wild Biology Catalysis Article Inorganic Chemistry Transcriptome lcsh:Chemistry 03 medical and health sciences Sea cucumber Aquaculture Animals Isostichopus badionotus Physical and Theoretical Chemistry Molecular Biology lcsh:QH301-705.5 Spectroscopy Impaired nutrient utilization business.industry Gene Expression Profiling Organic Chemistry Computational Biology Reproducibility of Results 04 agricultural and veterinary sciences General Medicine biology.organism_classification First generation Computer Science Applications Metabolic pathway 030104 developmental biology Gene Ontology lcsh:Biology (General) lcsh:QD1-999 aquaculture Animals Domestic 040102 fisheries gene expression 0401 agriculture forestry and fisheries business holothurids transcriptome sea cucumber Function (biology) |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 22, Iss 3882, p 3882 (2021) Volume 22 Issue 8 |
| ISSN: | 1422-0067 |
| Popis: | Overfishing of sea cucumber Isostichopus badionotus from Yucatan has led to a major population decline. They are being captured as an alternative to traditional species despite a paucity of information about their health-promoting properties. The transcriptome of the body wall of wild and farmed I. badionotus has now been studied for the first time by an RNA-Seq approach. The functional profile of wild I. badionotus was comparable with data in the literature for other regularly captured species. In contrast, the metabolism of first generation farmed I. badionotus was impaired. This had multiple possible causes including a sub-optimal growth environment and impaired nutrient utilization. Several key metabolic pathways that are important in effective handling and accretion of nutrients and energy, or clearance of harmful cellular metabolites, were disrupted or dysregulated. For instance, collagen mRNAs were greatly reduced and deposition of collagen proteins impaired. Wild I. badionotus is, therefore, a suitable alternative to other widely used species but, at present, the potential of farmed I. badionotus is unclear. The environmental or nutritional factors responsible for their impaired function in culture remain unknown, but the present data gives useful pointers to the underlying problems associated with their aquaculture. |
| Databáze: | OpenAIRE |
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