Two independent outbreaks of measles in partially vaccinated junior high schools in Tottori, Japan

Autor: T. Ozeki, T. Honda, H. Hayashibara, A. Kawamoto, K. Ishida, S. Hino, Kazuo Shiraki
Rok vydání: 1995
Předmět:
Zdroj: Archives of virology. 140(2)
ISSN: 0304-8608
Popis: We analyzed retrospectively a relative risk of measles attacks in vaccinated vs. unvaccinated students using two independent outbreaks in Japan. The first involved 33/328 (10%) students where 64% students and 30% measles cases had been vaccinated. The second involved 27/241 (11%) students where 81% students and 48% measles cases had been vaccinated. The attack rates of vaccinated vs. unvaccinated students were significantly low (p0.001), but they accounted 25% in both episodes. The statistically significant clinical features among vaccinated and unvaccinated cases included the average duration of fever, 5.16 +/- 1.71 vs. 6.67 +/- 2.19 days (p = 0.01) and the incidence of complications, 0 vs. 25%, respectively. These results suggested that the measles in vaccinated cases were mostly due to secondary failures.
Databáze: OpenAIRE