Global Asthma Network Phase I study in Mexico: prevalence of asthma symptoms, risk factors and altitude associations—a cross-sectional study
| Autor: | Philippa Ellwood, Luis Garcia-Marcos, Blanca Estela Del-Río-Navarro, Arturo Berber, Nayely Reyes-Noriega, Elsy Maureen Navarrete-Rodríguez, Roberto García-Almaraz, Omar Josué Saucedo-Ramírez, Valente Juan Mérida-Palacio, Beatriz Del Carmen Ramos-García, Alberto José Escalante-Domínguez, Francisco Javier Linares-Zapién, Héctor Leonardo Moreno-Gardea, Georgina Ochoa-López, Luis Octavio Hernández-Mondragón, José Santos Lozano-Sáenz, José Antonio Sacre-Hazouri, Ángeles Juan-Pineda, Ma Guadalupe Sánchez-Coronel, Noel Rodríguez-Pérez, María de Jesús Ambriz-Moreno, OJ Saucedo Ramírez, V Merida-Palacio, BC Ramos-García, AJ Escalante-Dominguez, F Linares-Zapien, HL Gardea-Moreno, G Ochoa-Lopez, LO Hernández-Mondragón, JS Lozano-Saenz, JA Sacre-Hazouri, A Juan-Pineda, MG Sánchez Coronel, N Rodríguez-Pérez, MJ Ambriz-Moreno |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pulmonary and Respiratory Medicine
Allergy Adolescent Cross-sectional study Protective factor lcsh:Medicine 03 medical and health sciences 0302 clinical medicine Altitude Risk Factors Wheeze medicine Prevalence Humans 030212 general & internal medicine Child Mexico Asthma lcsh:RC705-779 business.industry lcsh:R asthma epidemiology lcsh:Diseases of the respiratory system Atopic dermatitis paediatric asthma medicine.disease Rash Cross-Sectional Studies 030228 respiratory system medicine.symptom business Demography |
| Zdroj: | BMJ Open Respiratory Research BMJ Open Respiratory Research, Vol 7, Iss 1 (2020) |
| ISSN: | 2052-4439 |
| Popis: | BackgroundGlobal Asthma Network (GAN) was established in 2012 as a development to the International Study of Asthma and Allergies in Childhood to improve asthma care globally.ObjectiveTo survey asthma, allergic rhinitis and atopic dermatitis in primary and secondary school children and to investigate and evaluate its prevalence, severity, management and risk factors in Mexico.MethodsGAN Phase I is a cross-sectional, multicentre survey carried out in 15 centres corresponding to 14 Mexican cities throughout 2016–2019 using the validated Spanish language version of the GAN Phase I questionnaires. The questionnaires were completed by parents of 6–7-year-old primary school pupils (school children) and by 13–14-year-old adolescents.ResultsA total of 35 780 school children and 41 399 adolescents participated. Wheezing ever prevalence was 26.2% (95% CI 25.8% to 26.7%) in school children and 23.9% (95% CI 23.4% to 24.3%) in adolescents. The corresponding frequencies for current wheeze were 10.2% (95% CI 9.9% to 10.5%) and 11.6% (95% CI 11.2% to 11.9%). In school children, the risk factors for current wheeze were rhinitis (OR 4.484; 95% CI 3.915% to 5.134%) and rash symptoms (OR 1.735; 95% CI 1.461% to 2.059%). For adolescents, rhinitis symptoms (OR 3.492; 95% CI 3.188% to 3.825%) and allergic rhinitis diagnosis (OR 2.144; 95% CI 1.787% to 2.572%) were the most significant. For both groups, there was a negative relation with centres’ sea level altitude higher than 1500 m above mean sea level (pConclusionsThe most important risk factors for asthma symptoms in both age groups were the presence of rhinitis and rash symptoms or diagnosis. On the other hand, sea level altitude higher than 1500 metres was a protective factor. |
| Databáze: | OpenAIRE |
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