Natural products isolation studies of the paleoendemic plant species Nothofagus gunnii and Nothofagus cunninghamii
| Autor: | Thinley Gyeltshen, Jason A. Smith, Alex C. Bissember, Gregory J. Jordan |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Magnetic Resonance Spectroscopy
Avicularin Victoria Ayanin Flavonoid Pinosylvin Tasmania chemistry.chemical_compound Stilbenes Drug Discovery Botany Flavonoids Pharmacology Nothofagus chemistry.chemical_classification Biological Products biology Plant Extracts Terpenes Pinobanksin General Medicine biology.organism_classification Terpenoid Plant Leaves Galangin chemistry Fagales |
| Zdroj: | Fitoterapia. 156:105088 |
| ISSN: | 0367-326X |
| DOI: | 10.1016/j.fitote.2021.105088 |
| Popis: | The first natural product isolation studies of Nothofagus gunnii (Hook.f.) Oerst and Nothofagus cunninghamii (Hook.f.) Oerst have been undertaken. A previously unreported stilbene derivative, pinosylvin monoacetate, was isolated from the leaves of N. gunnii, in addition to 14 known compounds; including the flavonoids galangin, pinobanksin, catechin and quercetin; sesquiterpenoids such as, ilicol and (+)-β-costol acetate; 2,4-dihydroxy-6-methoxychalcone and pinosylvin. Four known flavonoid natural products, catechin, quercetin, ayanin, and avicularin were isolated from the leaves of N. cunninghamii. This study reveals that N. gunnii is a rich source of flavonoid, chalcone and stilbene compounds, while primarily hydroxyflavonoid compounds are found in N. cunninghamii. The isolated phytochemicals are consistent with the evolutionary relationships suggested to exist among Nothofagus species. |
| Databáze: | OpenAIRE |
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