Optical fiber sensors for monitoring in critical care
| Autor: | R Sinha, Sergiy Korposh, Ricardo Correia, Stephen P. Morgan, Barrie Hayes-Gill, F. U. Hernandez, Elena V. Piletska, Fabiana Grillo, LiangLiang Liu, A. Norris, Sergey A. Piletsky, Francesco Canfarotta |
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| Rok vydání: | 2019 |
| Předmět: |
Optical fiber
Materials science Critical Care business.industry Molecularly imprinted polymer Humidity Grating engineering.material Temperature measurement law.invention Refractometry Fiber Bragg grating Coating law Fiber optic sensor engineering Fiber Optic Technology Humans Optoelectronics business Refractive index Optical Fibers |
| Zdroj: | EMBC |
| Popis: | Monitoring of key physiological and pharmacological parameters is an important part of a closed loop control system in critical care. Optical fiber sensors provide a versatile platform technology that can be easily incorporated into existing in-dwelling catheters or face masks. With appropriate functional coatings they can be used to monitor a range of relevant parameters and two different examples are presented: (i) respiration monitoring; (ii) drug level monitoring. Respiration monitoring involves monitoring of temperature and humidity in inhaled and exhaled breath. The optical fiber sensor consists of a fiber Bragg grating to measure temperature and a tip coating whose refractive index changes with humidity. The sensor is demonstrated to be able to track breath to breath changes when incorporated into a mask. Drug level monitoring is demonstrated in vitro using a long period grating coated with molecularly imprinted polymer nanoparticles that are sensitive to fentanyl. The sensor has a limit of detection of 50ng/ml. |
| Databáze: | OpenAIRE |
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