Nasal Type Extranodal Natural Killer/T (NK/T) Cell Lymphoma Presenting as Periorbital Cellulitis: A Case Report
| Autor: | Shanmugam Ganesan, Mansour Al Sulaiti, Hamad Al Saey, Ma’in Ali Al Shawabkeh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Nose Neoplasms Nose neoplasm Dexamethasone Diagnosis Differential 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Antineoplastic Combined Chemotherapy Protocols Granulocyte Colony-Stimulating Factor medicine T-cell lymphoma Humans Ifosfamide Sinusitis Granuloma Lethal Midline Etoposide Mesna business.industry Periorbital cellulitis General Medicine Articles Orbital Cellulitis medicine.disease Prognosis Peripheral T-cell lymphoma Fungal sinusitis Lymphoma Extranodal NK-T-Cell Paranasal sinuses medicine.anatomical_structure Methotrexate Treatment Outcome 030220 oncology & carcinogenesis 030221 ophthalmology & optometry Orbital cellulitis business Paranasal Sinus Neoplasms |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| Popis: | Patient: Male, 25 Final Diagnosis: Nasal type • extra nodal NK/T-cell lymphoma Symptoms: Left periorbital swelling • redness • pain for 25 days • yellowish eye discharge associated • headache • fever Medication: — Clinical Procedure: — Specialty: Otolaryngology Objective: Unusual clinical course Background: Extranodal lymphoma of the paranasal sinuses is a rare clinical entity seen in only 5–8% of extranodal lymphomas of the head and neck. Nasal natural killer/T cell lymphoma (Nasal NKTCL), which is a subtype of peripheral T cell lymphoma, constitutes about 1.4% of all lymphomas. NKTCL is usually diagnosed at a late stage because it presents with nonspecific symptoms in the early stages. Case Report: We report the case of a 25-year-old male patient who presented with periorbital swelling treated as fungal sinusitis but proven to have NKTCL. We review the literature and discuss the clinical manifestations of the disease, its relation to EBV virus, the histological and radiological characteristics, the prognostic indicators, and treatment options. This case report shows physicians that NKTCL lymphoma can present as periorbital cellulitis, although few similar cases are found in the literature. Conclusions: NKTCL is a destructive midline tumor that should be kept in mind as a differential diagnosis of paranasal sinus lesions to help in early diagnosis, which can improve the prognosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|